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Gynecological Devices Market Key Players, Industry Overview and Forecast Analysis

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The global gynecological devices market is marked by a high degree of fragmentation due to the presence of several large and small manufacturers, reports Transparency Market Research (TMR) in a new business intelligence study. This leaves ample room for market consolidation in the near future. Nevertheless, top companies namely Boston Scientific Corporation, Cooper Surgical, and Olympus Corporation hold prominence on account of their extensive product portfolio and geographical outreach. These companies are vying to introduce non-invasive devices to serve a larger consumer base that will also help expand their geographical outreach. With increasing demand for medical help for women-centric health issues, there lies immense scope of growth for players in the gynecological devices market.

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At present, small as well as regional players hold significant share in the gynecological devices market. However, increasing entry barriers and stringent regulations for product approval are limiting the entry of new companies. Insufficient funding from venture capitalists is also challenging new companies to enter this market.

As per projections of a TMR report, the global gynecological devices market will clock 4.8% CAGR between 2017 and 2023. This will translate opportunities in the market to generate a revenue of US$22,589.9 mn by 2023 from US$17,015.9 mn in 2017. In terms of device type, gynecological surgical devices hold prominence in the market. Rising prevalence of single incision laparoscopic surgeries and advances in conventional endoscopic surgeries account for advances in gynecological surgical instruments. Geography-wise, North America is a lucrative market for gynecological devices due to the early adoption of advanced gynecological devices.

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Efforts of Global Health Organizations for Women Health a Boon for Market

First and foremost, rising incidence of gynecological disorders such as uterine fibroids, cervical cancer, and menorrhagia is driving the gynecological devices market. In developing countries, healthcare infrastructural development and technologically advanced diagnostic services is favoring the gynecological devices market. An increasing awareness among women in these countries regarding therapeutics for gynecological diseases is also stoking demand for gynecological devices. Global health organizations and non-profit organizations conduct periodic health check-ups in developing and underdeveloped countries for women health. This stokes demand for gynecological devices.

In urban areas, modern lifestyle and increasing professional and personal stress are also related to gynecological conditions. This is necessitating routine check-up for women-centric health issues that may require gynecological devices at secondary stage of therapeutics.

Rising Preference for Minimally Invasive Procedures Stokes Demand

At present, acceptance of minimally invasive procedures generally is on the rise. This is because minimally invasive surgeries involve shorter hospital stay and faster recovery. Minimal scarring and ease of post-surgery care are leading individuals to opt for minimally invasive procedures. Gynecological surgery at one time meant big painful incisions, longer recovery periods, and intense monitoring. Due to this, open exposure surgical hysterectomies is increasingly being replaced with minimally invasive hysterectomies that involve the use of an electric morcellator surgical device.

Increasing public and personal healthcare expenditures and rising awareness of therapeutics for gynecological diseases in developing countries is cementing the growth of this market. Women health in these countries is increasingly being considered important for economic development thus drawing the attention of national governments.

However, long hauls for product approval and delays for product approval from regulatory authorities is providing headwinds to the growth of gynecological devices market. Stringent documentation and compliance requirements delay commercial availability of advanced first-mover products.

posted Feb 11 by Rohini Chaudhari

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In Vitro Toxicology Testing Market: Introduction

  • Toxicology or toxicity, also known as ‘the science of poisons,’ is a method of testing the opposing effects of any drug, chemical or other agent administered in the body. It, thus, analyses the adverse effects of various toxins on all living organisms. 
  • In vitro toxicology testing does not make use of whole animals or whole organisms. It rather uses tissue slices, isolated organs, cell lines isolated primary cell cultures, explants cultures, and subcellular fractions such that of mitochondria and membranes.
  • In vitro toxicology testing also helps in determining the drug safety profile at an early stage, thus saving a considerable amount of time and resource investment

Report overview @ https://www.transparencymarketresearch.com/in-vitro-toxicology-testing-market.html

Key Drivers and Restraints of Global In Vitro Toxicology Testing Market

  • Scientific concerns over animal experiments have been raised in the field of toxicology testing. It entails problems such as difference between various test animals and resultant effects of toxicants, characterization of actions of these toxins on different animals, and categorization of test animals on the basis of their biology and effects of toxins.
  • Animal testing has been in effect since long; however, the implementation of in vitro toxicology testing is an alternative to animal testing. It is effective and harmless as compared to animal testing.
  • In vitro toxicology is cost effective and growing ethical concerns worldwide are expected to drive the in vitro toxicology market during the forecast period. Pharmaceutical companies are, thus, increasingly shifting their focus from animal testing to in vitro toxicology testing.
  • Advantages of in vitro toxicology testing over traditional methods of animal testing in terms of quick turnaround time and better sample control will also help the global market to grow at a rapid rate
  • Opposition to animal testing will have a major impact on the in vitro toxicology testing market, as animal testing will be reduced to a large extent 

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Cellular Assay Technology Segment to Lead Global In Vitro Toxicology Testing Market

  • In terms of technology, the global in vitro toxicology testing market can be divided into cellular assay, biochemical assay, in silica, and ex-vivo
  • In the present scenario, cellular assay methods are widely used by industries in safety assessment, risk evaluation, and toxicity testing. The cellular assay method is mainly used to elucidate mechanisms of toxicity in a drug and its effect on a cell or a tissue.

Pharmaceutical Industry Segment to Offer Growth Opportunities

  • Based on end-user, the global in vitro toxicology testing market can be categorized into cosmetics & household products, pharmaceutical industry, food industry, and chemicals industry
  • Pharmaceutical industry is estimated to be a highly lucrative segment. Pharmaceuticals play a major role in in vitro toxicology testing, as the test is to identify the toxicity of various chemical drugs and their effects on the human body. Chemicals are used in various products, which has a direct or indirect effect on the human body .Thus, in vitro toxicology can be useful in finding the toxic nature of such chemicals and their effects on the human body.

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North America to Lead Global In Vitro Toxicology Testing Market

  • The global in vitro toxicology testing market can be divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is a significant market for in vitro toxicology testing due to the presence of several key market players.
  • Substantial investments in research and development by various end-user segments in the region are anticipated to drive the global in vitro toxicology testing market in North America

Key Players Operating in Global In Vitro Toxicology Testing Market

Key players operating in the global in vitro toxicology testing market are:

  • Abbott Laboratories
  • Bio-Rad Laboratories, Inc.
  • Agilent Technologies, Inc.
  • Cyprotex
  • Charles River Laboratories, Inc.
  • Covance, Inc.
  • Thermo Fisher Scientific, Inc.

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Reperfusion Injury Market: Description

Reperfusion injury is referred to as the tissue damage caused due to absence of blood supply or lack of oxygen such as damage to brain after stroke or heart post episodes of ischemia. Such kind of restoration of blood supply results into inflammation and oxidative damage through the induction of oxidative stress rather than normal functioning. Confined infarct size and reduced mortality can be achieved by prompt restoration of blood supply to myocardium. However, this restoration is also known to result in the cardiac damage and eventually reperfusion injury. A delay in reperfusion therapy has been attributed for such damage. 

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Reperfusion of ischemic tissue is often associated with microvascular injury. The duration for which a tissue can survive deprived of oxygen varies, but eventually the tissue is rendered necrotic. The blood supply restoration usually minimizes the damage, but reperfusion of tissue post thrombolytic procedures demonstrated that the extent of injury often increased on restoration of the blood supply. The studies have also attributed this reperfusion injury, to the activity of free radicals.

Reperfusion Injury Market: Segmentation

The global reperfusion injury market can be segmented based on therapy type, injury type and geography. Drugs used for treating reperfusion injury are classified on the basis of mode of action, target site, route of administration and molecule type. Geographically, the global reperfusion injury market can be categorized into four major regions namely, North America, Europe, Asia-Pacific and Rest of the World. Primary percutaneous coronary intervention (PCI) and thrombolysis, form the primary reperfusion therapies and are often used for treating acute coronary syndromes.

Reperfusion Injury Market: Overview

Allopurinol, one of the drugs in clinical trials helps inhibit production of free radicals thereby known to reduce the size of infarct. However the drug has not been universally successful. An enzyme called recombinant superoxide dismutase has been under investigation as free radical scavenger that detoxifies oxygen.

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Various other drug molecules in clinical trials include cyclosporine, MTP-131, bucillamine, recombinant proteins, type 5 adenylyl cyclase inhibitors, and synthetic peptides amongst others. Agents that specifically target proteins, transcription factors or ion channels, including PPAR, PKC agonists/antagonists, Phosphodiesterase-5 inhibitors, the ATP-dependent potassium channel and 3-Hydroxy-3-methyl glutaryl coenzyme A reductase are also promising.

However, currently no agent has been clinically approved for treatment of reperfusion injury. Studies demonstrating success in the clinical use have been disappointing for last few years though successful results have been observed on animals. The unclear solutions and lesser potential therapies that limit the free radicals generation on reperfusion are also under investigation in several clinical trials. New avenues for investigation are recently opened due to studies demonstrating involvement of inflammatory cytokines and their effects on neutrophiles.

Additionally, a combination of better techniques for rapid reperfusion and use of neutrophil inhibitors and anti-oxidants will help in reduction of the enormous cost associated with the clinical trials for treatment of reperfusion injury. Other options under study for treatment of reperfusion injury include hypothermia treatment, post conditioning such as mechanical and pharmacologic have shown success in few patients.

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Larger experiments exploring the potential of various therapeutic options in order to influence clinically relevant endpoints are yet awaited for options which are currently insufficiently demonstrated in clinical use of these reperfusion injuries.

Reperfusion Injury Market: Companies Mentioned in the Report

Apeptico Forschung und Entwicklung GmbH, Eustralis Pharmaceuticals Ltd., NeuroVive Pharmaceutical AB, Nyken BV, Stealth Peptides, Inc., Scynexis, Inc., and Vasade Biosciences, Inc. are some of the key players contributing to the global reperfusion injury market.

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According to the recent report by Transparency Market Research, the global autoimmune disease diagnostics market has a highly consolidated scenario. The market is dominated by a handful of players. However, these players have a stronghold over the dynamics of market and pose a great challenge for any new entrant to set its foot in the market. To reduce effects of such hindrances, the new entrants are focusing on schemes such as mergers,  collaborations, and partnerships. These strategies provide necessary resources to the new players so that they can have a sustainable future in the global autoimmune disease diagnostics market.

On the other hand, the established players are focusing on strategies such as innovative product launches, intense research and developments, and various other steps in order to maintain their dominance in the global autoimmune disease diagnostics market. A few of the players are also adopting strategies like acquisition of various small and medium-scale businesses in order to expand their resource bank and brand presence across regional markets of the world.

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According to the report, the global autoimmune disease diagnostics market is projected to exhibit a moderate growth with 3.8% CAGR in the forecast period of 2015 to 2023. Moreover, the global autoimmune disease diagnostics market is projected to reach the value of US$17.06 bn by the end of 2023.

  • Increasing Elderly Population to Boost the Growth of Rheumatoid Arthritis Segment

The global autoimmune disease diagnostics market is segmented on the basis of disease type, test type, and region. Out of these categories, rheumatoid arthritis segment under disease type category is expected to exhibit maximum growth in the global autoimmune disease diagnostics market. The growth of the segment is attributed to parameters such as rising number of aging population and enhanced diagnostic services.

  • North America is likely to Show Maximum Potential during the Forecast

Geographically, the global autoimmune disease diagnostics market has its presence in region of North America, South America, Europe, Asia Pacific, and Middle East and Africa. Out of these regions, North America is expected to showcase high scope for players in the market. The growth of the region is attributed to the presence of majority of major players and novel developments in healthcare sector in North America.

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Rising Investment in Healthcare Sector to Boost the Growth of the Market

  • Growing Healthcare Expenditure to Promote the Growth of Market

As a result of growing economy of various regions, there is a substantial growth in disposable income of the people. This allows them to invest significantly in their healthcare expenditure especially in autoimmune treatments. This in turn is supporting the growth of global autoimmune disease diagnostics market in the forecast period.

  • Supporting Government Initiatives to Help the Growth of the Market

Growing support from governments of various countries and various government initiatives to widespread the awareness of autoimmune diseases is one of the most prominent factors that is supporting the growth of global autoimmune disease diagnostics market.

Despite of Numerous Growth Factors, Market is Expected to Face Many Challenges

  • Shortcoming of Professional Operatives to Dampen the Growth of the Market

The growth of autoimmune disease diagnostics market is supported by various parameters. However, there are some tough challenges in the road to success for players in the market. One of the major challenges that players might have to deal with is the unavailability of skilled professionals who can do precise diagnosis of the disease. This may lead to an error filled result impacting drastically on the health of the patient. Due to this reason, the growth of global autoimmune disease market is likely to get hamper in the forecast period.

  • Various New Markets in the Emerging Economies Are Offering Better Opportunities

There are several challenges that are expected to hamper the growth of global autoimmune disease diagnostics market in the forecast period. However, factors such as new emerging economies, innovative product launches by various players, and intense research and development to replace conventional treatment for autoimmune diseases are likely to support the global autoimmune disease diagnostics market. In this way the challenges could be overcome up to a certain extent.

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Spine Augmentation Systems Market:  Introduction

  • Spine augmentation systems can be defined as devices that perform minimally invasive vertebral surgical procedures. Spine augmentation systems are used for pain management, owing to vertebral compression fractures. These systems are used to make cavity within the vertebral body before the injection of cement during the process of minimally invasive surgical procedure to soothe fractures. Moreover, these augmentation systems are used to conduct various types of surgical procedures: vertebroplasty, balloon kyphoplasty, and others.
  • The global spine augmentation systems market is anticipated to expand at a rapid pace during the forecast period, owing to incessant rise in geriatric population, high prevalence of osteoporosis, and market availability of comprehensive product line of spine augmentation systems.

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Key Drivers of Global Spine Augmentation Systems Market

  • Increase in percentage of geriatric and obese population is likely to propel the adoption of spine augmentation systems during the forecast period. According to the U.S. Department of Health & Human Product, the geriatric population in the U.S. will reach 72.1 million by 2030. This is expected to be a key factor driving the global spine augmentation systems market during the forecast period.
  • Prevalence of these degenerative spine conditions has been increasing and is known to be of common occurrence in population. According to the WHO, 80% to 90% of the U.S. population is affected by degenerative spine diseases; their symptoms ranging from back pain to severe limitations in mobility. Hence, rise in prevalence of spinal diseases is likely to contribute to the growth of the global spine augmentation systems market.
  • Awareness among people about various spinal disorders and available treatments has been increasing. There has been a rise in the number of dedicated websites providing information related to spine diseases and their treatment. Moreover, this awareness is boosting the adoption of spinal fusion devices. This factor is expected to fuel the global spine augmentation systems market during the forecast period.

High Risks Associated with Surgeries Hamper Spine Augmentation Systems Market

  • Almost every spinal surgery is linked with complications and risks. These risks may often lower the benefits associated with spinal surgeries resulting in hampering the spine augmentation systems market growth. Major risks associated with these surgeries include failure to release lower back pain symptoms. This surgical outcome is usually known as “failed back surgery syndrome”.
  • Spinal surgeries majorly lead to changes in the functioning of spine, shifting the stress from fused vertebrae to adjacent areas of the spine. This may cause wear and tear of vertebral joints resulting in further chronic pain and damage. Some other risks associated with spinal surgeries include nerves damage, incisional site infection, anesthetic complications, and bleeding, among others.  This factor is likely to hinder spine augmentation systems market growth during the forecast period.

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Asia Pacific to Hold a Major Share of Global Spine Augmentation Systems Market

  • Asia Pacific is a leading consumer of spine augmentation systems, followed by North America and Europe. China and India are key markets in the region. The two countries account for a combined share of 30% of the demand for spine augmentation systems in the region.
  • Increase in population, rise in incidences of orthopedic diseases, and improving economy of China, India, and others countries of Southeast Asia are resulting in high per capita health care expenditure. This is anticipated to drive the spine augmentation systems market in the region.
  • The spine augmentation systems market in Middle East & Africa is estimated to expand at a rapid pace during the forecast period. This can be attributed to rise in investments in the health care industry of the region.

Key Players Operating in Global Spine Augmentation Systems Market:

The global spine augmentation systems market is highly competitive with top manufacturers adopting various strategies for attaining maximum market share. Some of the key players operating in the global spine augmentation systems market are:

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  • Alphatec Spine
  • Amendia
  • Biopsybell
  • BM Korea
  • CLARIANCE

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The global market for neonatal intensive care holds commendable growth opportunities for market players in the contemporary times. The demand for neonatal intensive care has been rising which has assisted the growth of the market players. The leading market players in the global market for neonatal intensive care have been making ardent efforts to ensure that their position in the market is not compromised. Furthermore, these market players have also been focusing on producing the most effective and efficient systems for prenatal intensive care. It is expected that the cumulative efforts of all the leading players would amount to an increased level of competition in the global market.

The smaller players have not proved their mettle in the global market and are yet to make major breakthroughs with regards to product innovation. It is anticipated that the medium and small-sized players would join hands to challenge the supremacy of the larger players. Furthermore, it is also projected that the larger market players would aim to strengthen the barriers to the entry of new players in order to keep reigning over the market. Some of the key players in the global market for neonatal intensive care are Teleflex Incorporated, B. Braun Melsungen AG, C. R. Bard, Inc., and Becton, Dickinson and Company. These market players have done especially well attracting the healthcare sector towards their products and offerings.

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The global neonatal intensive care market is projected to expand at a respectable CAGR of 5.50% over the period between 2017 and 2025. Furthermore, the global market is expected to stand at a net worth of  US$9.0 bn by the end of 2025 as against a value of US$5.9 bn in 2017. Based on geography, the global market for neonatal intensive care is expected to be led by North America.

Rising Incidence of Disorders and Diseases in New-borns to Drive Demand

The field of neonatal care has been making key advancements in recent times as the need for better care of new-borns has increased. The number of new-born kids who suffer from several kinds of diseases and disorders has also increased in recent times, and this has pushed demand within the global market for neonatal intensive care. Furthermore, the medical practitioners, doctors, and specialists have been focusing on the need for better neonatal care in order to ensure that the child is prevented from acquiring infection or diseases. This has given an impetus to the growth of the global market for neonatal intensive care. The government has also been pressing hospitals and healthcare centers to ensure proper treatment of infants and protecting them from hospital-acquired infections.

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Respiratory Devices to Emerge as Leading Segment

Based on the type of products, respiratory devices have clocked in the highest demand in recent times. Several new born babies are seen to suffer from respiratory problems during their initial days due to a variety of reasons. It is also true that the demand for respiratory devices in neonatal intensive care has escalated due to the need for respiratory aids in women.

The global market for neonatal intensive care holds commendable growth opportunities for market players in the contemporary times. The demand for neonatal intensive care has been rising which has assisted the growth of the market players. The leading market players in the global market for neonatal intensive care have been making ardent efforts to ensure that their position in the market is not compromised. Furthermore, these market players have also been focusing on producing the most effective and efficient systems for prenatal intensive care. It is expected that the cumulative efforts of all the leading players would amount to an increased level of competition in the global market.

The smaller players have not proved their mettle in the global market and are yet to make major breakthroughs with regards to product innovation. It is anticipated that the medium and small-sized players would join hands to challenge the supremacy of the larger players. Furthermore, it is also projected that the larger market players would aim to strengthen the barriers to the entry of new players in order to keep reigning over the market. Some of the key players in the global market for neonatal intensive care are Teleflex Incorporated, B. Braun Melsungen AG, C. R. Bard, Inc., and Becton, Dickinson and Company. These market players have done especially well attracting the healthcare sector towards their products and offerings.

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The global neonatal intensive care market is projected to expand at a respectable CAGR of 5.50% over the period between 2017 and 2025. Furthermore, the global market is expected to stand at a net worth of  US$9.0 bn by the end of 2025 as against a value of US$5.9 bn in 2017. Based on geography, the global market for neonatal intensive care is expected to be led by North America.

Rising Incidence of Disorders and Diseases in New-borns to Drive Demand

The field of neonatal care has been making key advancements in recent times as the need for better care of new-borns has increased. The number of new-born kids who suffer from several kinds of diseases and disorders has also increased in recent times, and this has pushed demand within the global market for neonatal intensive care. Furthermore, the medical practitioners, doctors, and specialists have been focusing on the need for better neonatal care in order to ensure that the child is prevented from acquiring infection or diseases. This has given an impetus to the growth of the global market for neonatal intensive care. The government has also been pressing hospitals and healthcare centers to ensure proper treatment of infants and protecting them from hospital-acquired infections.

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Respiratory Devices to Emerge as Leading Segment

Based on the type of products, respiratory devices have clocked in the highest demand in recent times. Several new born babies are seen to suffer from respiratory problems during their initial days due to a variety of reasons. It is also true that the demand for respiratory devices in neonatal intensive care has escalated due to the need for respiratory aids in women.

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