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Contrast Media Market Development, Trends, Segmentations Analysis

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Transparency Market Research (TMR) has published a new report titled, “Contrast Media Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2018–2026”. According to the report, the global contrast media market was valued at US$ 4,600 Mn in 2016 and is projected to expand at a CAGR of 4% from 2018 to 2026. The report suggests that rise in awareness among people about pre-diagnosis of diseases such as cancer and cardiovascular is expected to drive the global market during the forecast period.

North America and Europe are anticipated to dominate the global contrast media market in the next few years owing to increase in installed base of imaging equipment and high health care spending. Asia Pacific is expected to be the fastest growing market by 2026. This is attributed to increase in geriatric population and rise in awareness about benefits of pre-diagnosis in developed countries such as Japan and Australia. Development of novel contrast media and advanced contrast media injectors is likely to fuel the growth of the global market. The market in Asia Pacific is projected to expand at a CAGR of 3% to 4% from 2018 to 2026.

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High Prevalence of Cancer and Cardiovascular Diseases to Drive Global Market

High prevalence of cancers such as breast cancer is a major factor fueling the growth of the global contrast media market. Increase in popularity of pre-diagnosis of breast cancer and colorectal cancer using imaging equipment is another factor anticipated to drive the global market during the forecast period. Rise in cardiovascular diseases that require identification of high risk patients and implementation of disease management made possible through medical imaging are the other factors expected to boost the growth of the global market from 2018 to 2026.

Furthermore, strong R&D, upcoming pipeline imaging drugs, and increase in health care spending are the factors likely to augment the global market during the forecast period. Stringent regulatory scenarios and adverse effects of contrast media in large number of patients are projected to restrain the global contrast media market from 2018 to 2026.

Iodine-based Compounds and Intravenous/Intra-arterial Segments to Dominate Global Market

The report offers detailed segmentation of the global contrast media market based on type, route of administration, imaging modality, and application. In terms of type, the iodine-based compounds segment is poised to account for leading share of the global market during the forecast period from 2018 to 2026. Factors attributed to the higher share of the segment include early detection of diseases including cancer, detection of asymptomatic heart diseases, and low osmolality of the compounds.

The iodine based compound segment accounted for over 30% share of the global market in terms of revenue in 2017. Based on route of administration, the global market has been classified into oral, rectal, intravenous/intra-arterial, and others. The intravenous/intra-arterial segment dominated the global market, accounting for over 30% share in 2017. The oral segment is expected to grow at a rapid pace during the forecast period due to increase in usage of oral contrast agents for gastrointestinal tract imaging.

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CT / X-ray and Cardiology Segments to Dominate the Market

In terms of imaging modality, the global contrast media market has been categorized into CT/X-ray, ultrasound, MRI, and others. The CT/X-ray segment is projected to account for the largest share of the global market in 2017 due to increase in installed base of CT scanners. Based on application, the global market has been divided into oncology, cardiology, neurology, and others. The cardiology segment is expected to capture the largest share of the global market due to high prevalence of cardiac diseases and increase in awareness about early detection. The segment held nearly 30% share of the global market in 2017. The others segment held the second largest share of the market in 2017, owing to rise in prevalence of other diseases such as gastrointestinal disorders and renal disorders.

Asia Pacific to be Fastest Growing Market

In terms of region, the global contrast media market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America held the largest share of the global market in 2017 and is projected to dominate the market during the forecast period from 2018 to 2026. The market in the region is anticipated to expand at a CAGR of 3% to 4% from 2018 to 2026. Well-established health care infrastructure and strong support from public and private sector in terms of reimbursements are expected to contribute to North America’s high market share.

Rise in awareness about prevention of diseases has led to improvements in diagnosis. This is likely to drive the market in the region during the forecast period. Europe is projected to account for the second largest share of the global contrast media market by 2026. The market is the region is anticipated to expand at a CAGR of 4% from 2018 to 2026. The market in Europe has matured due to introduction of new technologies. However, contrast agents such as MRI-based agents are witnessing significant growth in the region in terms of revenue.

Asia Pacific is the fastest growing market for contrast media. The market in the region is likely to expand at a CAGR of 4% to 5% during the forecast period. Increase in population, rise in prevalence of cardiovascular diseases, and surge in musculoskeletal problems are the major factors fueling the growth of the market in the region. Australia, Japan, India, and China are the potential markets for contrast media in Asia Pacific. The market in China is expected to expand at the fastest CAGR during the forecast period due to rise in disposable income and increase in funding for R&D. The contrast media market in Middle East & Africa is projected to expand at a CAGR of 3% to 4% from 2018 to 2026. Investment by major players in the region is anticipated to propel the market.

posted Feb 11 by Rohini Chaudhari

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The demand within the global contrast media injectors market has witnessed an upsurge on account of advancements in the field of radiology, estimates Transparency Market Research (TMR). The market players in the global market for contrast media injectors have been on the lookout for effective marketing strategies that can help them in attracting a larger consumer base. It is expected that the global market for contrast media injectors would undergo successive fragmentation as new and emerging players establish their strongholds in the market.

The leading players in the global market for contrast media injectors have successfully acquired a few smaller players over the past decade. These key market players are projected to continue with their strategy of dominance through acquisition as challenges for the smaller players multiply. Furthermore, the global market is projected to witness a series of mergers in the coming years as the market players open their doors to collaborations and partnerships. The sustenance of new players in the global market for contrast media injectors is severely challenged by the strategic alliances formed by the leading market players. Some of the key players in the global market for contrast media injectors are Mallinckrodt Pharmaceuticals, Bracco Imaging S.p.A., Medtron AG, Nemoto Kyorindo, and VIVID IMAGING.

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The global contrast media injectors market is expected to expand at a moderate CAGR of 5.0% over the period between 2014 and 2020. Furthermore, the market value is projected to be worth USD 886.7million in 2020 as against a value of USD 630.1 million in 2013. Based on geography, the market for contrast media injectors in North America is expected to outdo all other geographical segments.

Need for CT Scans and MRIs to Propel Demand

The medical imaging of important medical scans such as MRI, CT/PET, and ultrasounds is enhanced with the help of contrast media injectors. This has become a key driver of demand within the global market for contrast media injectors and is expected to fetch greater demand over the forthcoming years. Medical practitioners have been on a quest to reduce medical errors by fostering precision, accuracy, and meticulousness during diagnosis and treatment of diseases. This has necessitated the use of contrast media injectors that help in getting a clearer and more distinct view of the internal body organs. Owing to this factor, the global market for contrast media injectors is projected to experience a regular inflow of demand over the coming years. However, the reluctance of the masses towards the use of contrast media injectors could act as a roadblock to market growth.

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Medical Tourism Bodes Well for Regional Markets

The medical industry of several emerging economies such as India and China has become accustomed to the use of contrast media injectors in recent times. This has created demand within the market for media injectors in Asia Pacific and has given an impetus to the growth of the regional vendors. Furthermore, the market for media injectors in North America has also witnessed boisterous growth over the past decade, majorly due to the advanced facilities for medical imaging available across the US and Canada.

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The Asperger syndrome is a type of developmental disorder known as autistic spectrum disorder (ASD). These disorders start during childhood and remain with people until they grow up. Children with the Asperger syndrome work healthier to those with an autism disorder, and they have typical knowledge and language advancement. In spite of the fact that they may create issues while imparting language as they get older. Side effects of the Asperger syndrome include redundant practices, abnormal distractions or ceremonies, constrained scope of interests, issues with social abilities, communication challenges, and coordination issues. The etiology of Asperger syndrome is unidentified; however, it is considered to be inherited. The genetic mutations expected to cause Asperger syndrome have not yet been identified.

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According to statistics provided by the World Health Organization (WHO), around 1 in every 160 children has autism spectrum disorder (ASD). Proof based psychosocial treatments such as training programs and behavioral treatments can decrease challenges in communication and social conduct in ASD patients. It is noticed that expanding innovative headways, government-supported awareness programs for extreme introvertedness, and rise in prevalence of autism spectrum disorder (ASD) and related inconveniences are the key factors driving the global Asperger disorder market.

Rise in awareness about Asperger syndrome, increase in number of patients with the syndrome, unmet medical needs, improving regulatory guidelines, surge in government support, and rise in financing and repayment drive the global Asperger syndrome market. However, symptoms related with the medications, strict FDA controls, and poor health care insurance framework in low- and middle-income areas are expected to restrain the market.

The global Asperger syndrome market can be segmented based on diagnosis, treatment, and end-user. In terms of diagnosis, the global market can be classified into DSM-IV, differential diagnosis, Gilliam Asperger’s Disorder Scale (GADS), childhood Asperger syndrome test, Krug Asperger’s Disorder Index (KADI), and others.

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The differential diagnosis segment can be categorized into schizophrenia spectrum, nonverbal learning disorder, Tourette syndrome, major depressive disorder, stereotypic movement disorder, personality disorder, social anxiety disorder, obsessive-compulsive disorder, pragmatic semantic disorder, bipolar disorder, and others. Based on treatment type, the global Asperger syndrome market can be divided into parent education & training, social skills training, speech-language therapy, applied behavioral analysis (ABA), sensory integration/occupational therapy, and medication.

The medicines segment dominated the market in 2017. The segment can be classified into various drug classes such as antipsychotics, selective serotonin reuptake inhibitors, psychiatric agents, and others. Antipsychotics include risperidone, paliperidone, and aripiprazole. Selective serotonin reuptake inhibitors include fluvoxamine, fluoxetine, sertraline, paroxetine, citalopram, and escitalopram. Psychiatric agents include atomoxetine and guanfacine.

In terms of end-user, the global Asperger syndrome market can be classified into clinics, hospitals, drug stores, pharmacies, diagnostic centers, and others. Hospitals is expected to be a highly lucrative segment owing to preference for treatment in these settings.

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Geographically, the global Asperger syndrome market can be segmented into Asia Pacific, North America, Western Europe, Eastern Europe, Latin America, and Middle East & Africa. North America is expected to dominate the market owing to increase in awareness about autism spectrum disorder (ASD).

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Neurotrophic Keratitis Market: Introduction

Transparency Market Research has published a new report titled, “Global Neurotrophic Keratitis Market”. According to the report, the global neurotrophic keratitis market was valued at US$ 91.6 Mn in 2018 and is projected to expand at a CAGR of ~17% from 2019 to 2027. Rise in reported cases of keratitis, increase in research & developmental activities, surge in awareness, and rise in co-morbidities & risk factors boost the growth of the global neurotrophic keratitis market.

Pharmacotherapies using Drugs to Lead Global Market

In terms of treatment type, the drugs segment accounted for major share of the global neurotrophic keratitis market in 2018. The segment is anticipated to witness strong growth from 2019 to 2027. The drugs segment has been sub-segmented into artificial tears, recombinant human nerve growth factor eye drop, antibiotics, bandage contact lens, and others. The artificial tears sub-segment accounted for major share of the drugs segment in 2018. However, the recombinant human nerve growth factors eye drops sub-segment is expected to account for major share by 2027, as these eye drops restore the normal healing process of the eye and repair corneal damage. The drugs segment’s major market share is due to increase in clinical studies, approvals, and launch of various novel products. In February 2019, ReGenTree initiated the ARISE-3 study, the phase 3 clinical trial of the new drug RGN-259 for the treatment of dry eye syndrome. In August 2018, Dompé announced the U.S. Food and Drug Administration (FDA) approval for cenegermin (Oxervate), a breakthrough therapy for neurotrophic keratitis (NK), which is a rare and progressive eye disease that can lead to corneal scarring and vision loss.

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Stage II Neurotrophic Keratitis to Remain Significant

Based on application, the stage I segment held major share of the global neurotrophic keratitis market in 2018. However, the stage II segment is projected to capture the largest share of the global market by 2027. Dominance of the stage I segment in 2018 can be ascribed to off-label availability of products for stage I, high prevalence of early symptoms in stage I, and high demand for preservative-free artificial tears during the first half of the forecast period. Symptoms of stage II neurotrophic keratitis help in diagnosis of the disease. A study published in 2014 titled, “Diagnosis and management of neurotrophic keratitis”, stated that stage II NK is characterized by recurrent and/or persistent epithelial defects (PED) with an oval or circular shape, most frequently localized at the superior half of the cornea. Diagnosis of NK is primarily based on the clinical history of conditions associated with trigeminal impairment, presence of PED or ulcers, and decreased corneal sensitivity.

A study published in Elsevier, Inc. in November 2017 indicated that around 34% of total studied patients in Italy were affected by persistent epithelial defects (PED) of stage II. Hence, the growth of the stage II segment can be ascribed to rise in awareness about and rate of diagnosis of the disease, launch of products which are effective in stage II persistent epithelial defects treatment, and surge in inclination of patients toward specialized centers for receiving advanced treatment.

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Neurotrophic Keratitis Market: Prominent Regions

North America held the largest share of the global neurotrophic keratitis market in 2018. The market in the region is projected to grow at a rapid pace during the forecast period, driven by presence of key players, technological advancements, and highly structured healthcare industry. Increase in clinical trials, product launches, and approvals, and rise in investment by key players are projected to propel the neurotrophic keratitis market in North America. The U.S. is anticipated to dominate the neurotrophic keratitis market in the region during the forecast period, owing to early adoption of technologies. The country is expected to be the most attractive market for neurotrophic keratitis treatment products, with high attractiveness index. Well-equipped hospitals, technological advancements, rise in research & development on neurotrophic keratitis for novel treatment and appropriate cure, and surge in demand for novel products & treatments are likely to augment the neurotrophic keratitis market in the U.S.

Neurotrophic Keratitis Market: Key Players

Key players in the global neurotrophic keratitis market focus on strengthening their positions in the global market. Players are collaborating with other companies, actively conducting research studies, participating in mergers & acquisitions, and increasing product approvals and launches to secure and strengthen their positions in the global neurotrophic keratitis market. In April 2019, Neuroptika announced positive data from the company's phase 1 clinical trial to determine the safety, tolerability, and pharmacokinetics of topical NRO-1 in healthy subjects. NRO-1 is a novel therapeutic, with the potential to protect and regenerate corneal nerves in ophthalmic diseases. In July 2017, Dompé announced that the European Commission had granted marketing authorization of cenegermin eye drops for the treatment of moderate to severe neurotrophic keratitis.

Major players operating in the global neurotrophic keratitis market include Dompe farmaceutici S.p.A., Allergan, ReGenTree, LLC, Alcon, Bausch & Lomb Incorporated (Bausch Health Companies Inc.), CONTACARE, ROHTO Pharmaceutical Co., Ltd., Pfizer, Inc., Neuroptika, Santen Pharmaceutical Co., Ltd., Johnson & Johnson, Grand Pharma (China) Co., Ltd., and Zhejiang CONBA Pharmaceutical Co., Ltd.

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Global Stable Isotope Labeled Compounds Market: Overview

Stable isotope-labeled compounds have generated considerable interest among researchers engaged in metabolism-mediated toxicity studies. Their role has risen in significance in assessment of in vivo metabolism in a vast range of metabolic research. The use of technologies such as mass spectrometry (MS) or nuclear magnetic resonance (NMR) has further expanded the research. These technologies have enabled researchers make better utilization of stable isotope labeled compounds for evaluating drugs’ disposition and their toxicity profile before they are used on patient populations.

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Their role has been rising in mechanistic toxicity studies as stable isotope-labeled compounds serve as a useful tool to enrich drug delivery research world over. Thus, they play a pivotal role in the management of several diseases, notably cancer and diabetes. Common stable isotope labeled compounds are 2H (Deuterium or D), 13C, 15N and 18O. Apart from metabolomics studies, stable isotope-labeled compounds are being increasingly used in environmental analysis, proteomics, and medical diagnostic research.

The report offers takes a critical and closer look at the current outlook and sheds light on emerging frontiers. The study findings are likely to form a useful guide for investors to identify lucrative avenues. The analyses of various growth dynamics in the stable isotope labeled compounds market helps emerging and established players to find out potential sources of revenue.  

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Global Stable Isotope Labeled Compounds Market: Trends and Opportunities          

Rising body of research on the pharmaceutical and biotechnology industries is a key factor underpinning the rapid evolution of the stable isotope-labeled compounds market. In developed countries, investments in proteomics research have risen in recent years. Growing prevalence of various cancer types in several parts of the world is a key factor bolstering the demand for stable isotope-labeled compounds. Moreover, various drug toxicity studies have risen in volumes with the aim of developing effective therapeutics and diagnostics.

Numerous emerging markets have been attractive sizeable investments in pharmaceutical research and development. Moreover, the high cost of stable isotope-labeled compounds may be a deterrent factor crippling the market prospects. Moreover, there is paucity of technical expertise for conducting pharmaceutical and biomedical research using stable isotope-labeled compounds.

Stable isotope-labeled compounds hold a large, promising potential in dynamic assessment of vivo metabolism in the paediatric population. Rising focus on accelerating the validation of new treatment modalities in order to reduce morbidity and mortality in pediatric populations is a key trend boosting the market.

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Global Stable Isotope Labeled Compounds Market: Regional Outlook

On the regional front, developed regions such as North America and Europe, are expected to generate substantial chunks in the global stable isotope-labeled compounds market. The growth in these regions is fueled by rapid advances in nutrition and metabolic research. Particularly, in the U.S., stable isotope-labeled compounds are witnessing large-scale production. In Canada, surging demand for stable isotope-labeled compounds is increasingly propped by advances being made in positron emission tomography technique. Developed regions are also likely to hold vast potential in the next few years. Presence of a few globally prominent players in North America who conduct extensive quality testing for these compounds reinforces large revenue potential of the region.  

Global Stable Isotope Labeled Compounds Market: Competitive Landscape

Several players are also focusing on bolstering their supply chains. Key companies vying for substantial shares in the stable isotope-labeled compounds include Nordion, Omicron Biochemicals, Inc., Medical Isotopes, Inc., IsoSciences, LLC., Cambridge Isotopes Laboratories, Inc., and Merck KGaA.

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The global electrophoresis equipment and supplies market is experiencing innovations, technological advancements, and availability of varied products, states a recent report by Transparency Market Research. The key players in electrophoresis equipment and supplies market are Hoefer Inc., Bio-Rad Laboratories Inc., GE Healthcare Ltd., and Life Technologies Corp. Of these players, the market experienced dominance of Bio-Rad Laboratories Inc., which accounted for over 50% of the overall market in 2012. Bio-Rad Laboratories Inc. is considered one of the most profound and strongest players in the market and has a stronger base and a stronger holding in the market.

The market has also been marked with several new players in the past few years and this has significantly increased the level of competition in the market. As the technologies central to electrophoresis equipment continue to evolve, the market is expected to get stiffer for new entrants. According to the report, the global electrophoresis and supplies market is expected to rise to a valuation of US$1.9 bn by 2019, expanding at a 4.80% CAGR over the forecast period.

Improved Disposable Income a Driver for Asia Pacific Region

Based on technology, the market has been covered in the report for gel electrophoresis market, capillary electrophoresis, and electrophoresis accessories. Of these, the segment of gel electrophoresis presently dominates and is expected to rise to a valuation of US$909.1 mn by 2019. The high demand for the technology can be attributed to its increased usage in the field of genomics.

According to geography, North America is the leading regional market and has continued to account for the dominant share in the overall market over the years due to increasing rate of innovation and development of new products. Europe stands at the second position, followed by Asia Pacific. It has been observed that emerging economies from Asia Pacific, such as India, China, Brazil, and Mexico, have shown improvement in the healthcare sector owing to rising government interventions and increase in disposable incomes of the population.

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Since the past few years, a number of companies from North America have outsourced their research for drugs and clinical trials to countries in Europe and Asia Pacific. As a result, the market for electrophoresis equipment and supplies also witnessed steady rise in Europe and Asia Pacific.

Move from Genomics to Proteomics to Boost Growth in Near Future

Growth of the global electrophoresis equipment and supply market could be propelled by the shift from genomics to proteomics, leading to technological advancement that further added to sensitivity, higher output, and increased resolution. The advancements in proteomics market have improved the global electrophoresis equipment market. In addition to this, innovations in drug development activities and therapies have been triggering further research in drug manufacturing, thus driving the increased demand for electrophoresis equipment and supplies.

Innovation and development in research areas have grown the limits in this field, on the other hand, however, the lack of newer techniques in equipment technology, has paved the way for substitutes in the market. Furthermore there is high demand for drug discovery research as there is an increasing demand for innovative drugs and therapies.

The other trend is the increasing set of applications of electrophoresis equipment in molecular profiling in the recent years. It also proposes reliable demand for electrophoresis technique. The hemoglobin electrophoresis technique was renowned as the most exact, precise, and frequently used technique for DNA analysis.

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