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Tauopathies Treatment Market Size, Share, Trend and Industry Analysis Report

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Tauopathies Treatment Market: Introduction

  • As per the NCBI (National Center for Biotechnology Information), tauopathies are described as neurodegenerative disorders caused by abnormal deposition of tau protein in the brain. Major tauopathies disorders include Pick’s disease, corticobasal degeneration, argyrophilic grain disease, and progressive supranuclear palsy. Emerging tauopathies disorders are primary age-related tauopathy including neurofibrillary tangle dementia, chronic traumatic encephalopathy (CTE), and aging-related tau astrogliopathy.

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  • Moreover, globular glial tauopathies in which tau is further characterized by astrocytic inclusions and globular tau-reactive oligodendroglial are considered as emerging tauopathies disorders. The globular glial tauopathies is further classified into three sub-types based on distribution of inclusions. Clinical symptoms of tauopathies include frontotemporal dementia, pure akinesia, Richardson syndrome, Parkinsonism, corticobasal syndrome, and motor neuron symptoms of cerebellar ataxia. In some neurodegenerative disorders, specific image of tau deposition is captured due to neuroimaging features. Tauopathies also occur due to novel concept of cell to cell distribution process.
  • Proper diagnosis is required to diagnose these neurodegenerative disorders in patients, for which cost-effective screenings are recommended. Thus, examination of amygdala, hippocampus, and basal ganglia is widely preferred by the neurosurgeons. Ongoing clinical trial and research would help understand cause and treatment of the tauopathies condition in the near future.

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Key Drivers and Restraints of Global Tauopathies Treatment Market

  • Ongoing research & development to develop drugs for tauopathies treatment is likely to be a driving factor for the market at global level. Increase in investments and rise in health care spending by the government are a few attributable growth factors. As per research, currently, no approved treatments are available for tauopathies protein found in neurodegenerative diseases, although as per research, the first approved drug would be a boon for the tauopathies treatment.
  • Regulatory approval process and supportive reimbursment policies are likely to setup therapeutic approach for tauopathies treatment. The clinical trials on developing farnesyltransferase inhibitor and disease-modifying drugs are expected to drive the global market in the next few years. However, the research is a time consuming process and currently no approved drugs are present in the market. These factors are expected to restrain the tauopathies treatment market.

North America to Lead Global Tauopathies Treatment Market

  • In terms of region, the global tauopathies treatment market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa
  • North America is projected to dominate the tauopathies market during the forecast period, owing to established research & development, investments in the late stage clinical development of drugs for tauopathies, supportive health care expenditure, government initiatives, and diagnosis of symptoms of tauopathies. Rise in incidence of neurodegenerative diseases such as Alzheimer’s and Parkinson’s; and presence of pharmaceutical and research companies in the region are likely to boost the tauopathies treatment market. Moreover, surge in health care expenditure, advanced health care facilities, and expanding contract research organizations in the market are anticipated to boost the growth of the tauopathies market in the region.
  • Europe is estimated to hold the second largest share of the global market in the next few years, followed by Asia Pacific. Diagnosis of tauopathy condition in 20 neurodegenerative diseases and investments by pharmaceutical companies and governments for research & development of treatment are expected to drive the market in Europe. Furthermore, rise in awareness about tauopathies treatment and initiatives by the government are likely to fuel the growth of the tauopathies treatment market in Asia Pacific region.

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Key Manufacturers Operating in Global Tauopathies Treatment Market

The global tauopathies treatment market consists of only a few players including pharmaceutical and small clinical stage companies involved in drugs development for treating tauopathies. Some of these players are:

  • Avanir Pharmaceuticals, Inc.
  • Otsuka Pharmaceutical Co., Ltd
  • AB Science
  • TauRx
  • Sellas
  • Catalent Inc.

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posted Feb 11 by Bella Watson

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Transparency Market Research (TMR) has published a new report titled ‘Hyperpigmentation Disorders Treatment Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2018–2026.’ According to the report, the global hyperpigmentation disorders treatment market was valued at US$ 3,947.3 Mn in 2017 and is projected to reach US$ 7,225.6 Mn by 2026, expanding at a CAGR of 7.2% during the forecast period from 2018 to 2026. The report suggests that augmented adoption of lasers in hyperpigmentation disorders treatment, decrease in social taboos boosting acceptance of pigmentation disorders treatment measures, increase in prevalence of pigmentation related disorders, rise in awareness about skin rejuvenation, improving lifestyle, and increasing disposable income are likely to drive the hyperpigmentation disorders treatment market from 2018 to 2026.

Despite its considerable patient population globally, the hyperpigmentation disorders treatment market has often been overlooked and has remained stagnant for the past few decades, with no novel drugs entering the arena. The lack of dedicated research programs has been attributed to pharmaceutical companies viewing topicals, the mainstay of hyperpigmentation disorders treatment therapy, as being inexpensive with a poor return on investment. Instead, the market has shifted towards reformulations of existing products and/or fixed-dose combination therapies. Examples of the latter include combination products by key dermatology players, such as Galderma’s Tri-Luma (fluocinolone acetonide/hydroquinone/tretinoin).

Request PDF Sample of Hyperpigmentation Disorders Treatment Market Report @ https://www.transparencymarketresearch.com/sample/sample.php?flag=S&rep_id=46644

Innovative products in hyperpigmentation disorders should focus on cost-effectiveness, potential to improve compliance. The biggest unmet needs in hyperpigmentation disorders include the need for new and innovative products, for improved compliance, and for less expensive products relative to existing therapies. Historically, pharmaceutical companies have been reluctant to enter the hyperpigmentation disorders market due to the poor return on investment in this competitive landscape. This attitude has inhibited progress toward developing disease-modifying agents, and agents with more long-lasting effects. However, the hyperpigmentation disorders treatment landscape is expected to change in the near to long term, with the use of laser and phototherapy, and additional companies involved in research for innovative acne products.

The report offers detailed segmentation of the global hyperpigmentation disorders treatment market based on treatment type, disease indication, end-user, and region. In terms of treatment type, the topical drugs segment is estimated to account for a large share of the market. An increasing number of patients with hyperpigmentation disorders are visiting dermatologists, and topical drugs are being prescribed to these patients.

Topical Drugs to Account for Major Share

The topical drug segment is expected to account for a leading share of the market in 2026. The segment is also likely to expand at a rapid pace during the forecast period. Rapid growth in the incidence rate of hyperpigmentation disorders across the globe will lead to an increased number of patients who will undergo diagnosis in the form of topical drugs and chemical peel, as well as treatment using techniques such as laser and phototherapy. This will in turn increase the uptake of hyperpigmentation disorders treatment, thereby driving growth of the market.

Enquiry for Discount on “Hyperpigmentation Disorders Treatment Market” Report @ https://www.transparencymarketresearch.com/sample/sample.php?flag=D&rep_id=46644

Market in Asia Pacific to Expand at a Significant Pace

Asia Pacific held a prominent share of the global hyperpigmentation disorders treatment market in 2017. The hyperpigmentation disorders treatment market in Asia Pacific is expected to expand at a rapid pace mainly due to improving health care infrastructure, rising private and public investment in life science research, and technological advancements in countries such as China and India. Less competition in Asia Pacific is encouraging a large number of dermo-cosmetics companies to enter the market.

U.S. market has witnessed significant technological advancements, as clinics come with laser and phototherapy treatment. In addition, a large number of market players in the U.S. are focusing on R&D to introduce improved products. Moreover, high awareness about latest health care technologies and high demand for safe and hyperpigmentation disorders products, services and devices to boost the hyperpigmentation disorders treatment market in North America. Favorable reimbursement policies in the region also enable patients to avail of the best of health care facilities.

Key Players such as ALLERGAN, Galderma S.A., and SkinCeuticals to Lead the Market

The report also provides profiles of leading players operating in the global hyperpigmentation disorders treatment market. They include include Bayer AG, ALLERGAN, Galderma S.A., SkinCeuticals, Pierre Fabre, EpiPharm AG, RXi Pharmaceuticals Corporation, Obagi Cosmeceuticals LLC, and Vivier Pharma. Corporate trend is the strategic acquisition of key dermatology products by Big Pharma. A notable event in 2009 involved the acquisition of Stiefel, a leading dermatology company, by GSK for $3.6 billion.

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Transparency Market Research (TMR) has published a new report titled ‘Hyperpigmentation Disorders Treatment Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2018–2026.’ According to the report, the global hyperpigmentation disorders treatment market was valued at US$ 3,947.3 Mn in 2017 and is projected to reach US$ 7,225.6 Mn by 2026, expanding at a CAGR of 7.2% during the forecast period from 2018 to 2026. The report suggests that augmented adoption of lasers in hyperpigmentation disorders treatment, decrease in social taboos boosting acceptance of pigmentation disorders treatment measures, increase in prevalence of pigmentation related disorders, rise in awareness about skin rejuvenation, improving lifestyle, and increasing disposable income are likely to drive the hyperpigmentation disorders treatment market from 2018 to 2026.

Despite its considerable patient population globally, the hyperpigmentation disorders treatment market has often been overlooked and has remained stagnant for the past few decades, with no novel drugs entering the arena. The lack of dedicated research programs has been attributed to pharmaceutical companies viewing topicals, the mainstay of hyperpigmentation disorders treatment therapy, as being inexpensive with a poor return on investment. Instead, the market has shifted towards reformulations of existing products and/or fixed-dose combination therapies. Examples of the latter include combination products by key dermatology players, such as Galderma’s Tri-Luma (fluocinolone acetonide/hydroquinone/tretinoin).

Request PDF Sample of Hyperpigmentation Disorders Treatment Market Report @ https://www.transparencymarketresearch.com/sample/sample.php?flag=S&rep_id=46644

Innovative products in hyperpigmentation disorders should focus on cost-effectiveness, potential to improve compliance. The biggest unmet needs in hyperpigmentation disorders include the need for new and innovative products, for improved compliance, and for less expensive products relative to existing therapies. Historically, pharmaceutical companies have been reluctant to enter the hyperpigmentation disorders market due to the poor return on investment in this competitive landscape. This attitude has inhibited progress toward developing disease-modifying agents, and agents with more long-lasting effects. However, the hyperpigmentation disorders treatment landscape is expected to change in the near to long term, with the use of laser and phototherapy, and additional companies involved in research for innovative acne products.

The report offers detailed segmentation of the global hyperpigmentation disorders treatment market based on treatment type, disease indication, end-user, and region. In terms of treatment type, the topical drugs segment is estimated to account for a large share of the market. An increasing number of patients with hyperpigmentation disorders are visiting dermatologists, and topical drugs are being prescribed to these patients.

Topical Drugs to Account for Major Share

The topical drug segment is expected to account for a leading share of the market in 2026. The segment is also likely to expand at a rapid pace during the forecast period. Rapid growth in the incidence rate of hyperpigmentation disorders across the globe will lead to an increased number of patients who will undergo diagnosis in the form of topical drugs and chemical peel, as well as treatment using techniques such as laser and phototherapy. This will in turn increase the uptake of hyperpigmentation disorders treatment, thereby driving growth of the market.

Enquiry for Discount on “Hyperpigmentation Disorders Treatment Market” Report @ https://www.transparencymarketresearch.com/sample/sample.php?flag=D&rep_id=46644

Market in Asia Pacific to Expand at a Significant Pace

Asia Pacific held a prominent share of the global hyperpigmentation disorders treatment market in 2017. The hyperpigmentation disorders treatment market in Asia Pacific is expected to expand at a rapid pace mainly due to improving health care infrastructure, rising private and public investment in life science research, and technological advancements in countries such as China and India. Less competition in Asia Pacific is encouraging a large number of dermo-cosmetics companies to enter the market.

U.S. market has witnessed significant technological advancements, as clinics come with laser and phototherapy treatment. In addition, a large number of market players in the U.S. are focusing on R&D to introduce improved products. Moreover, high awareness about latest health care technologies and high demand for safe and hyperpigmentation disorders products, services and devices to boost the hyperpigmentation disorders treatment market in North America. Favorable reimbursement policies in the region also enable patients to avail of the best of health care facilities.

Key Players such as ALLERGAN, Galderma S.A., and SkinCeuticals to Lead the Market

The report also provides profiles of leading players operating in the global hyperpigmentation disorders treatment market. They include include Bayer AG, ALLERGAN, Galderma S.A., SkinCeuticals, Pierre Fabre, EpiPharm AG, RXi Pharmaceuticals Corporation, Obagi Cosmeceuticals LLC, and Vivier Pharma. Corporate trend is the strategic acquisition of key dermatology products by Big Pharma. A notable event in 2009 involved the acquisition of Stiefel, a leading dermatology company, by GSK for $3.6 billion.

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According to Transparency Market Research (TMR), the global mortuary equipment market has fragmented landscape as numerous local and global companies are offering services in the country. Some of the key players operating in the isothermal bags & containers market are Mopec and Kugel Medical GmbH. In 2014, both the companies held a share of more than 50% in the overall market. Thermo Fisher Scientific Inc., Mortech Manufacturing Inc., LEEC UK, Flexmort, and Ferno-Washington Inc. are some of the other prominent players in this market.

According to a report by Transparency Market Research (TMR), the global market is likely to witness a healthy rise in its valuation from US$173.4 mn in 2014 to US$306.0 mn by 2023, expanding at a CAGR of 6.30% during the period from 2015 to 2023. Although the future of the worldwide market for mortuary equipment is projected to be teeming with opportunities, it may face hurdles due the high cost of technically advanced equipment.

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Need for Better Preservation of Cadavers to Fuel Adoption   

The increasing investment by healthcare units and mortuaries for the procurement of high-quality mortuary equipment in order to provide better preservation of cadavers is propelling the global mortuary equipment market significantly. The augmenting need for well-preserved cadavers for forensic tests as well as in academic and commercial research is fueling the demand for advanced mortuary equipment across the world. The technical advancements, boosting the usability of mortuary equipment, is likely to lead to a remarkable rise in their sales over the next few years. 

Scope of Heightened Demand across New Applications in Forensics and Research Sectors to Bolster Growth Prospects

Technological advancements have helped bring in automation in the field of mortuary equipment. Companies are increasingly commercializing automated mortuary equipment that assist in safe and speedy operations with the minimal need for manual interference.

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Such automated equipment are allowing the global mortuary equipment market to foray into new application areas in the field of research and forensics. With a heightened level of usability and flexibility, the demand for advanced mortuary equipment is expected to soar in areas such as transportation of well-maintained corpses in commercial and academic research and forensic tests.

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The global market for neonatal intensive care holds commendable growth opportunities for market players in the contemporary times. The demand for neonatal intensive care has been rising which has assisted the growth of the market players. The leading market players in the global market for neonatal intensive care have been making ardent efforts to ensure that their position in the market is not compromised. Furthermore, these market players have also been focusing on producing the most effective and efficient systems for prenatal intensive care.

It is expected that the cumulative efforts of all the leading players would amount to an increased level of competition in the global market. The smaller players have not proved their mettle in the global market and are yet to make major breakthroughs with regards to product innovation. It is anticipated that the medium and small-sized players would join hands to challenge the supremacy of the larger players.

Furthermore, it is also projected that the larger market players would aim to strengthen the barriers to the entry of new players in order to keep reigning over the market. Some of the key players in the global market for neonatal intensive care are Teleflex Incorporated, B. Braun Melsungen AG, C. R. Bard, Inc., and Becton, Dickinson and Company. These market players have done especially well attracting the healthcare sector towards their products and offerings.

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The global neonatal intensive care market is projected to expand at a respectable CAGR of 5.50% over the period between 2017 and 2025. Furthermore, the global market is expected to stand at a net worth of  US$9.0 bn by the end of 2025 as against a value of US$5.9 bn in 2017. Based on geography, the global market for neonatal intensive care is expected to be led by North America.

Rising Incidence of Disorders and Diseases in New-borns to Drive Demand

The field of neonatal care has been making key advancements in recent times as the need for better care of new-borns has increased. The number of new-born kids who suffer from several kinds of diseases and disorders has also increased in recent times, and this has pushed demand within the global market for neonatal intensive care.

Furthermore, the medical practitioners, doctors, and specialists have been focusing on the need for better neonatal care in order to ensure that the child is prevented from acquiring infection or diseases. This has given an impetus to the growth of the global market for neonatal intensive care. The government has also been pressing hospitals and healthcare centers to ensure proper treatment of infants and protecting them from hospital-acquired infections.

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Respiratory Devices to Emerge as Leading Segment

Based on the type of products, respiratory devices have clocked in the highest demand in recent times. Several new born babies are seen to suffer from respiratory problems during their initial days due to a variety of reasons. It is also true that the demand for respiratory devices in neonatal intensive care has escalated due to the need for respiratory aids in women.

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Bone Substitutes Market – Introduction

Bone substitute is defined as a synthetic, biologically organic, or inorganic combination which is used in the treatment of bone defects. Various bone substitutes have been used in the past 50 years. Bone substitutes are primarily categorized into ceramics (TCP, hydroxyapatite, and calcium sulfate), bone grafts (xenograft, autograft, and allograft), and growth factors (PRP, DBM, BMPs). Ideal properties of a bone substitute include biocompatibility, thermally nonconductive, sterilizable, and should not evoke any adverse inflammatory response. Additionally, it should be osteoconductive, osteoinductive, and resorbable.

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Bone substitutes are widely used in orthopedic surgeries for a number of applications. Bone grafting is the second most frequent tissue transplantation procedure performed across the world. Over two million bone graft procedures are performed every year, with more than 500,000 implanted in the U.S. alone. This is due to ease of use & handling, improved safety profiles, intraoperative cost & time advantages, and adaptability with a variety of clinical challenges.

Bone Substitutes Market – Competitive Landscape

DePuy Synthes

Founded in 1895, DePuy Synthes is headquartered in Warsaw, Indiana. The company is the part of the Johnson & Johnson Family of Companies. DePuy Synthes offers comprehensive portfolio of orthopaedic and neuro products and services for joint reconstruction, trauma, spine, sports medicine, neuro, cranio-maxillofacial, power tools and biomaterials.

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Medtronic

Founded in 1949, Medtronic is a leading medical devices company engaged in the development, manufacturing, and marketing of products for alleviating pain and restoring normal health of patients

The company operates through four business segments: cardiac & vascular group, minimally invasive therapies group, restorative therapies group, and diabetes group

The Medtronic Orthopedic Solution offering products for total joint replacement is a part of company’s Spine division within the Restorative Therapies Group.

Zimmer Biomet

Established in 1927, Zimmer Biomet is a one of the prominent player in the medical device market catering to customers present in musculoskeletal health care arena

The company manufactures and markets orthopedic reconstructive products; sports medicine, biologics, extremities & trauma products; spine, bone healing, craniomaxillofacial & thoracic products; dental implants and related surgical products

The company’s offers its products to orthopedic surgeons; neurosurgeons; oral surgeons, dentists, hospitals, distributors, health care dealers and other specialists in orthopedic market

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Its products are used to treat injuries, bone, joint, and soft tissue disorders

The company operates in more than 25 countries worldwide, and its products are distributed in more than a 100 countries through its wide distribution network

Zimmer Biomet has over 8,000 patents related to technologies incorporated in its products.

Stryker

Founded – 1941, Kalamazoo, U.S. Stryker is a global medical device company offering its products in orthopedic implants, trauma, and replacement surgeries; endoscopic and communication systems; emergency medical equipment and intensive care disposable products; surgical equipment and surgical navigation systems; and other products.

The firm operates through three business segments: Orthopedics, MedSurg, and Neurotechnology and Spine. The orthopedic segment offers joint replacement products which includes brands like Mako Partial Knee, Mako Total Knee, and  Restoris MCK

As of December 2016, Stryker has registered over 2,184 U.S. patents and 3,454 international patents

The company offers its medical devices to customer in hospitals and other health care facilities in the U.S. It also offers products through subsidiaries and branches and other third-party dealers and distributors in more than 100 countries.

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Bone Substitutes Market – Dynamics

Increase in the number of cases of bone disorders across the world drives the global bone substitutes market

According to the International Osteoporosis Foundation, the global incidence of fractures is anticipated to increase by 240% in women and 310% in men by 2050. Moreover, increase in the geriatric population, rise in research & development expenditure, and surge in awareness among end-users contribute to the growth of the global bone substitutes market. The market is expected to witness significant demand during the forecast period. However, risk associated with immune response and disease transmission are the major factors hampering the growth of the global bone substitutes market. Moreover, stringent regulatory framework and high cost are the other factors restraining the market. Furthermore, ethical issues associated with bone harvesting hampers the growth of the global bone substitutes market in some regions

Asia Pacific to Remain a Forerunner in the Demand for Bone Substitutes

The market in Asia Pacific is projected to expand at a high CAGR during the forecast period, driven by large patient pool, increase in government initiatives, and developing health care infrastructure in India and China. The market in Latin America and Middle East & Africa is anticipated to be driven by increase in investments by leading players in these regions and rise in prevalence of orthopedic diseases.

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