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Cancer Cachexia Market Set for Rapid Growth and Trend, by 2025

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Current and ongoing clinical trials in oncology have shed light on multifactorial pathogenicity of the syndrome cancer cachexia. Understanding the mechanism of cancer cachexia has become imperative for the understanding of prognostic factors for cancer. Biopharmaceuticals seeking stronghold in the global cancer cachexia market have adopted strategies that accelerate time-to-market of novel pharmaceutical agents, observes analysts at Transparency Market Research.

Top Players Adopt Strategies for Testing Multidisciplinary Combination Therapies

Leading players are entering into partnerships and mergers with, and acquisitions of organizations engaging in clinical trials. These strategies underpin the development of new multidisciplinary combination therapies, thereby aiding them to consolidate their shares.In an increasingly competitive market, companies that vie for sizable shares in the cancer cachexia market include Novartis, Merck & Co. Inc., Eli Lilly and Co., Aphios Corp., Alder BioPharmaceuticals Inc., and Aeterna Zentaris.

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Advancing Oncology Care Reflects Well on North America Market

Among the various regions, the pipeline of pharmacologic agents is ripe in North America. The North America cancer cachexia market is expected to be at the forefront by 2025. Large part of the growth impetus comes from advancing paradigm of care for cancer patients. Further, the prevalence of cachexia in Japan and Europe will make these key cancer cachexia markets in the not-so-distant future.

In recent years, product pipeline for the wasting syndrome has strengthened in North America and Europe, thus imparting momentum to the cancer cachexia market. This is bolstered mainly by presence of pipeline drugs in phase 3 clinical trial.

Developing regions, notably Asia Pacific, have vast pool of patients with cancer. This is a robust factor underpinning research into understanding the etiology of underlying cancer cachexia. Of marked significance is understanding of myostatin/activin pathways, paving way for new avenues in the global cancer cachexia market.

Rich Drug Pipeline of Multiple Pharmacologic Agents boosts Market

The cancer cachexia market stood at US$1.63 bn and is projected to garner a CAGR of 4.90% from 2017 to 2025. By the end of this assessment period, opportunities in the market will climb to US$2.51 bn. The growth of the global cancer cachexia market is fueled by vast research on using multiple agents for treating metabolic abnormalities in cachexia. Development of these multiple pharmacologic agents will further gather steam on the back of regulatory landscape.

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Therapies that Prolong the Life of Patients Gather Steam

Countering weight loss in cancer cachexia is vital in improving the quality of life of patients. Most importantly, cancer cachexia is characterized by poor tolerance of antitumor treatments, notably to chemotherapy and radiotherapy; unhindered loss of muscle mass may even lead to death. More than half of the patients with cancer develop the symptoms of cachexia, thereby propelling the need for treatment modalities. Clinical research on therapies that prolong the life of the patient populations is a key trend propelling the expansion of the cancer cachexia market.

The cancer cachexia market will gather considerable momentum from the growing awareness about improving the life of cancer patients. Researchers have been seeking pharmacological treatments using diverse chemical compounds. In this regard, non-steroidal anti-inflammatory drugs (NSAIDs) have shown good promise.

Still, there is conspicuous lack of large studies that could establish the efficacy of any specific treatment, making the progress in the cancer cachexia market slightly slow. Nonetheless, in recent years, randomized trials have shed light on the growing potential of newer chemotherapy agents. Of special significance to this is the role of combination chemotherapy in the adjuvant setting to improve survival rates.

posted Feb 12 by Rohini Chaudhari

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The anti-infective viral drugs to witness robust growth as infectious diseases continue to rise amidst changing weather patterns globally. The prevalence of diseases like malaria, chikungunya, and chagas disease are also expected to drive demand for anti-infective viral drugs market in the near future.

According to WHO or the World Health Organization, Vector borne illnesses account for over 700,000 deaths annually. Moreover, these disease account for 17% of all the common infectious diseases. This affects over 3.9 billion people in over 128 countries with spread of illnesses like dengue and nearly a 100 million cases are estimated each year.

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Moreover, diseases like malaria have also seen massive global prevention efforts each year. Foundation like the Melinda and Bill Gates foundation has invested large sums of money in preventing diseases like Malaria. This disease causes more than 400,000 deaths each year and the global efforts are expected to drive significant demand for anti-infective viral drugs to counter the threat of the disease.

Moreover diseases like leishmaniasis, chagas disease, and schistosomiasis impact the lives of hundreds of millions each year globally. The spread of these diseases and investments in informed policy making for the prevention of these diseases are expected to drive significant growth for the anti-infective viral drugs market.

Anti-Malaria Drug Sales Jumped 76% in India

Sales of anti-malarial drugs jumped by 76% in Mumbai in 2019. The monsoon season prolonged in the region which led to heavy monsoons and unexpected burden on the healthcare system. The unexpected situation boosted the sales of the pharma industry significantly, which stood at meager 11.2% growth during July to September. It also resulted in 5.5% increase in prices while the volumes rose by 3.2 during the same period. The sales of drugs for vector-borne illnesses was the biggest positive for the market. Moreover, India is proving to be a major success for the prevention of malaria, which has witnessed lowered deaths by about 50% in recent years. The success of the program is likely to drive more growth in the future.

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Tropical and Sub-tropical Regions to Drive Growth

Vector-borne illnesses are mostly caused by viruses, parasites, and bacteria. These are often transmitted through sandflies, mosquitoes, blackflies, triatomine bugs, tsetse, lice, mites, snails, and ticks. The suitable climate for growth of various species and changing agricultural practices are leading to an enormous growth of some of these transmitting species and subsequent illnesses. Additionally, factors like rising urbanization, adequate solid waste management, and lacking reliable piped water. Recent outbreaks like Zika virus, prevalence of malaria, and worsening climatic conditions are expected to result in more health precautions, and overwhelm health systems in several nations. The rising initiatives by organizations like WHO to support countries, provide key information for prevention, and innovation in various key anti-infective viral drugs are expected to drive growth.

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A copious number of players operate in the global diabetes drugs market on account of entry barriers being low. This makes the landscape both fragmented and competitive. A recent report on the market published by Transparency Market Research predicts the competition to intensify further in the near term owing to the entry of more players and emphasis on product development by the existing ones. Regional expansion strategies of players via mergers and acquisitions and strategic alliances is another method by which players are growing their shares.

Some of the current key companies operating in the global market for diabetes drugs are Boehringer Ingelheim GmbH, Novo Nordisk A/S, Bayer AG, Novartis AG, Sanofi, and Merck & Co.

As per the report, the market would likely register a CAGR of 3.6% over the course of the forecast period between 2017 and 2025 to attain a value of US$ 58.4 bn by 2025-end from US$ 43.1 bn in 2016.

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Among the different type of diabetes, type 2 diabetes is at present is grossing maximum revenue in the global market for diabetes drugs. This is because of the increased occurrence of this particular category owing to the rising problem of obesity in urban pockets, bettering healthcare facilities and outreach, and increasing healthcare spends of people. From a geographical standpoint, North America holds a leading share because of unhealthy eating patterns and sedentary lifestyle of its people in general which has led to an alarming rise in the chronic ailment.

Sedentary Lifestyle, Resulting in Rising Diabetes Cases, Boosts Market

The global market of diabetic drugs is on the rise owing to the spike in the number of cases of diabetes – both type 1 and type 2. As per a recent report by WHO, around 422 million people worldwide suffer from diabetes. This number is four times that of the number of people afflicted with the disease in 1980. The report observes that even though the prevalence has increased worldwide, low- and middle-income countries are home to most of the diabetic population. While the causes of diabetes are complex and often difficult to find, obesity and lack of physical activities are known to definitely contribute to a degree.

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Diabetes of any kind can result in complications in many parts of the body and also up the risk of premature death. According to findings of WHO, in 2012 it claimed around 1.5 million lives all over the world. However, with regular physical activities and healthy diet, alongside proper medication such fallout can be prevented. Rising awareness about the same has served to boost the demand for diabetic drugs in the recent past.

Research and Development of More Effective Products Bodes Well for Growth

Another major factor contributing to the diabetic drugs market is the emergence of more effective products every now and then, thanks to the constant efforts by manufacturers and research institutions in this direction. A noticeable trend in the market is the substantial sales of diabetic drugs through hospital pharmacies. Other distribution channels resulting in sales are retail pharmacies and online pharmacies.

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The global medical imaging equipment market is moderately consolidated in nature and is expected to remain in the similar scenario throughout the forecast period, stated a new market research study by Transparency Market Research. Some of the leading players operating in the global market are Philips Healthcare, GE Healthcare, Siemens Healthcare, and CareStream Health, Inc. In 2014, the above mentioned players collectively accounted for a share of 51% of the global medical imaging equipment market. The healthy competition among the leading players in terms of cost of product will be seen in the next few years. The key players in the market are focusing on research and development activities for the expansion of product portfolio, which is likely to generate potential growth opportunities in the next few years.

According to the market research study by Transparency Market Research, in 2013, the global market for medical imaging equipment was worth US$27.70 bn. The market is projected to reach US$45.30 bn by the end of 2022, exhibiting a 5.60% CAGR between 2015 and 2023.

North America to Remain Dominant in Global Medical Imaging Equipment Market

Among the regional segments, North America is expected to witness a high growth throughout the forecast period. In the last few years, this region accounted for a large share of the global market and is projected to remain in this position for the next few years. The high growth of this region can be ascribed to the rising demand for enhanced imaging devices. In addition to this, the development of the healthcare infrastructure, which has resulted in a high demand for technologically-advanced medical imaging equipment is predicted to accelerate the growth of the overall market in the coming years. As per the research study, North America is anticipated to register a 4.60% CAGR between 2015 and 2023.

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The global medical imaging equipment market has been categorized on the basis of technology into ultrasound systems, magnetic resonance imaging equipment, computed tomography scanners, nuclear imaging equipment, and X-ray devices. Among these, the x-ray devices segment is expected to witness a high growth in the next few years. The increasing use of x-rays and its assistance in diagnosing a wide range of complicated diseases are the major factors that are anticipated to accelerate the growth of this segment in the next few years.

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Technological Advancements to Drive Global Medical Imaging Equipment Market

Technological advancements in the 3D imaging technology is one of the major factors estimated to encourage the growth of the global medical imaging equipment market in the next few years. The development in the computer-aided detection and the rising applications for imaging diagnostic applications are the some of the other key factors that are likely to drive the global market in the next few years. In addition to this, the increasing incidence of a large number of diseases, including orthopedic, respiratory, and cardiovascular is predicted to result in a high demand for medical imaging equipment throughout the forecast period.

On the other hand, the reduction in the budget of healthcare is anticipated to restrict the growth of the global medical imaging equipment market in the next few years. In addition, the rising awareness among doctors regarding the hazards of the radiations by imaging devices is estimated to curtail the growth of the market throughout the forecast period. Nonetheless, the rising prevalence of several chronic diseases is anticipated to generate promising growth opportunities for the market players across the globe.

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According to the new research report published by Transparency Market Research, the global IoT in healthcare market is on course to achieve a stellar growth in coming years of the forecast period. The competitive landscape of the global market is extremely intense and is one of the reasons behind its overall development. The leading players in the global IoT in healthcare market are projected to pool in their resources for the fuelling the activities of research and development. Some of the other leading vendors in the market are concentrating on inorganic marketing strategies such as collaborations, joint ventures, mergers, and acquisitions to expand their business operations.

Increasing Focus on In-patient Monitoring

A key trend that has been emerging in the global IoT in healthcare market is the growing focus on the solutions of in-patient monitoring. For instance, GE Healthcare recently launched a wide range of product portfolio for in-patient monitoring. In it, there are new equipment for networking, cuff accessories, care ports, and patient monitors. Such developments are expected to propel the global IoT in healthcare market to newer heights.

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Some of the leading companies in the global market for internet of things in healthcare market include names such as Medtronic Inc., Honeywell International Inc., IBM Corporation, General Electric Company (GE Healthcare), and Microsoft Corporation among others.

As per the research report, the global IoT in healthcare market is will exhibit a massive CAGR of 20.6% for the given forecast period of 2017 to 2025. With this massive growth rate, the valuation of the global market is estimated to reach the mark of US$322.77 bn by end of 2025.

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Interconnectivity Platforms Have Helped in Market Growth

The healthcare sector has benefitted hugely because of the recent technological developments. The rise of technology that interconnects important medical devices and equipment has been particularly helpful for the development of the healthcare sector. These devices are mainly used for patient notification in case of emergency or abnormalities, observing patterns, reading, and patient monitoring among other activities. The technology is also deployed for making informed decisions and monitoring of risks. One of many important driving factors for the global market have been the growing use of the connected technology in the healthcare domain for the management of clinical tasks and operational workflow. It has presented the market players with an opportunity to develop a platform to note the potential system downtime by automating the alert system.

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Transparency Market Research (TMR) has published a new report titled, “Bioremediation Technologies and Services Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2019–2027”. According to the report, the global bioremediation technologies and services market was valued at US$ 37.8 Bn in 2018 and is projected to expand at a CAGR of 8.0% from 2019 to 2027. Increase in funding by governments, growing environmental concerns, and rising adoption of novel bioremediation techniques are anticipated to drive the global therapy technologies market from 2019 to 2027.

Overview

  • Bioremediation is process that uses naturally occurring organisms that help in the breakdown of hazardous substances into nontoxic or less toxic substances. Bioremediation is that it does not use chemicals and it allows the waste to be recycled once the contamination is removed or neutralized.
  • It is applicable for many applications such as soil preservation, waste water treatment, air pollution, radioactive hazard treatment, etc.  Increasing awareness about water scarcity in the future, and government regulations & initiatives for environmental sustainability drives the market growth rate by 2027.

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Governments of Developed and Emerging Nations Are Emphasizing On Monitoring and Tackling the Contamination Issues in Various Countries to Drive Market

  • Increasing hazardous wastes and remediation of these wastes is a major concern worldwide. Thus, governments of developed and emerging nations are emphasizing on monitoring and tackling the contamination issues in various countries to secure the future generations from resource scarcity.
    • The U.S. Army Corps of Engineers has taken initiatives to treat the explosives-contaminated groundwater using the approach of bioremediation. The federal agency is using microorganisms to break down the explosive contaminants in Washington area.
  • Organizations such as Natural and Accelerated Bioremediation Research (NABIR) and the Biological and Environmental Research (BER) financially support the fundamental research activities to promote ecofriendly approaches of reducing soil and water contamination
    • In India, prevention and control of water and soil pollution by promoting bioremediation have been the prioritized agenda of the Ministry of Environment and Forests (MoEF), a government organization
    • The Environment Protection Authority (EPA) is an agency of the U.S. government that aims to evaluate and treat the contaminated areas at a global level. In recent years, efforts of the EPA are reflected through its significant multilateral partnerships in the corporate world, aiming to improve the global climate and future environmental health outcomes. The EPA conducts the Superfund program for cleaning up the most contaminated areas in the U.S

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Fungal Remediation Segment to Dominate Market

  • In terms of technology, the global bioremediation technologies and services market has been bifurcated into phytoremediation, biostimulation, bioaugmentation, bioreactors, fungal remediation, and land-based treatments.
  • The fungal remediation segment is expected to dominate the global bioremediation technologies and services market during the forecast period due to increase in use of mycelium to disintegrate contaminants from waterways, soil or even radioactive contaminated areas. This will increase the usage of fungus for treatment procedures of soil which are being polluted by mercury & other heavy metals.

Wastewater Remediation to be Highly Attractive Segment

  • In terms of services, the global bioremediation technologies and services market has been classified into soil remediation, wastewater remediation, oilfield remediation, and others.
  • The wastewater remediation segment is likely to dominate the global bioremediation technologies and services market during the forecast period due to increase in decentralized approach (traditional end-of-pipe solutions) to treat the selected wastewater streams has driven demand among industries and agriculture.
  • According to UNESCO, high-income countries treat about 70% of the wastewater that these generate, while that ratio drops to 38% in upper middle-income countries and to 28% in lower middle-income countries.
  • In low-income countries, only 8% of industrial and municipal wastewater undergoes treatment. However, decline in disposal costs and development of existing & new wastewater treatment technologies for optimizing resource consumption is anticipated to drive the bioremediation technology & services market during the forecast period.

Asia Pacific Market to Expand Significantly

  • In terms of revenue, North America is projected to dominate the global bioremediation technologies and services market from 2019 to 2027. This can be ascribed to presence of major manufacturing industries and rise in research and development activities in the region. The following factors are directly impacting the growth and development of bioremediation technology & services.
  • However, rise in the number of companies offering bioremediation services as well as new product launches in the region is also a major factor driving the growth in market share of the North America segment.
  • The region is expected to continue to dominate the market in the forecast period due to the rise in funding by local governments for bioremediation-related research.
  • The demand for bioremediation services is increasing owing to rapid technological advances and services offered by industries such as EcoNow.
  • In May 2017, Ecosciences, Inc., a company based in New York, announced the launch of EcoNow, a new brand offering of bioremediation tablets. The product utilizes the company’s Oxy-Tab technology that offers a large number of beneficial bacteria, buffers, and oxygen, which break down solids, waste, paper, and grease in order to remove build-up in drains and pipes and maintain the septic tank.
  • The bioremediation technologies and services market in Asia Pacific is anticipated to expand at a significant CAGR during the forecast period. This can be attributed to the public–private partnerships for bioremediation-related activities and government initiatives for river conservation through bioremediation explore new markets opportunities, especially in Asia Pacific, to increase their revenue and market share.

Competitive Landscape in Global Bioremediation Technologies and Services Market

  • The report also provides profiles of leading players operating in the global bioremediation technologies and services market. These include Altogen Labs, Aquatech International LLC, Drylet, LLC, InSitu Remediation Services Limited, Ivey International, Inc., PROBIOSPHERE Inc., REGENESIS, Sarva Bio Remed, LLC, Sevenson, Environmental Services, Inc., Soilutions Ltd, Sumas Remediation Services Inc., Xylem Inc.; and Others.
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