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Osteoarthritis Drugs Market: Lucrative Opportunities

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The global osteoarthritis drugs market is witnessing various innovations on the horizons such as rapid pain relieving injections and disease modifying drugs, thanks to growing cases of major illnesses like obesity. The global osteoarthritis is expected to witness a robust competition as the market landscape continues to be increase in fragmentation. Major players in the market are making large investments in reseach and development globally, finds Transparency Market Research (TMR). Some key players in the global osteoarthritis drugs market are Pfizer Inc., Horizon Pharma plc, Ferring B.V., Sanofi, Anika Therapeutics, Inc., Chugai Pharmaceutical Co., and Bioventus, Inc.

The global osteoarthritis drugs market is expected to be propel forward in the near future, thanks to a growing awareness of diseases like degenerative bone disease, increasing R&D, and growing geriatric population as well. The pharmaceutical industry is growing through a tough phase as several key patents have expired. On the other hand, the industry is also faced with opportunities to reduce manufacturing costs considerably, due to advancements like 3D printing, several lucrative outsourcing opportunities, and prospects like Nano technology. This is expected to act as a catalyst for innovation in the industry with several firms already raising the bar with new drug developments and vital modifications in processes.

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The global osteoarthritis drugs market is projected to touch US$ 11,226.1 mn by 2026 end. However, due to patent expiry challenges and introduction of several generic versions driving down margins, the market is likely to expand at a single digit CAGR during the forecast period. Among various types of drugs in the market, the viscosupplementation agents are expected to dominate market growth, partly due to their high costs and partly due to growing demand for knee related arthritis treatments due to their effectiveness.

Growing Elderly Population a Major Driver of the Osteoarthritis Drugs Market

Osteoarthritis (OA) is an prevalent disease globally and it affects the elderly population quite severely. The condition is also life-threatening to many as it leads to impaired mobility leading to more potential accidents and financial constraints. However, the current crop of osteoarthritis drugs only offer pain mitigation and relief, but not a permanent solution. Additionally, osteoarthritis drugs also fail to halt disease progression. Hence, despite their lack of effectiveness and extreme high costs of viscosupplementation, the global osteoarthritis drugs market continues to grow. Moreover, the rising elderly population around the globe, and increasing reach of programs like Medicare in the US and privatized healthcare bill recently introduced in Australia, the osteoarthritis drugs market will result in several new opportunities for innovation.

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Anti-Nerve Growth Therapy Promises a New Avenue for Growth

The global osteoarthritis market is witnessing several new product launches like increased investments, increasing prevalence of osteoarthritis due to growing obesity worldwide, and this has resulted in promising treatments like Anti- NGF treatments. NGF or Nerve Growth Factor is a promising therapy which can subside the progression of several arthritic conditions, and provides immense relief during chronic pain. Additionally, advent of other disease modifying osteoarthritis drug (DMOAD) also presents a new opportunity on the horizon. These drugs have proven to improve key functions like joints and promise to halt the progression of the disease as well. Nanobody is another promising treatment for arthritis.

However, lack of seriousness in treating arthritis differently than conditions like old age is a major factor restraining the growth of the market. More awareness and more promising drugs can be major impetus for growth for the osteoarthritis drugs market in the near future.

posted Feb 12 by Rohini Chaudhari

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The anti-infective viral drugs to witness robust growth as infectious diseases continue to rise amidst changing weather patterns globally. The prevalence of diseases like malaria, chikungunya, and chagas disease are also expected to drive demand for anti-infective viral drugs market in the near future.

According to WHO or the World Health Organization, Vector borne illnesses account for over 700,000 deaths annually. Moreover, these disease account for 17% of all the common infectious diseases. This affects over 3.9 billion people in over 128 countries with spread of illnesses like dengue and nearly a 100 million cases are estimated each year.

Moreover, diseases like malaria have also seen massive global prevention efforts each year. Foundation like the Melinda and Bill Gates foundation has invested large sums of money in preventing diseases like Malaria. This disease causes more than 400,000 deaths each year and the global efforts are expected to drive significant demand for anti-infective viral drugs to counter the threat of the disease.

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Moreover diseases like leishmaniasis, chagas disease, and schistosomiasis impact the lives of hundreds of millions each year globally. The spread of these diseases and investments in informed policy making for the prevention of these diseases are expected to drive significant growth for the anti-infective viral drugs market.

Anti-Malaria Drug Sales Jumped 76% in India

Sales of anti-malarial drugs jumped by 76% in Mumbai in 2019. The monsoon season prolonged in the region which led to heavy monsoons and unexpected burden on the healthcare system. The unexpected situation boosted the sales of the pharma industry significantly, which stood at meager 11.2% growth during July to September. It also resulted in 5.5% increase in prices while the volumes rose by 3.2 during the same period. The sales of drugs for vector-borne illnesses was the biggest positive for the market. Moreover, India is proving to be a major success for the prevention of malaria, which has witnessed lowered deaths by about 50% in recent years. The success of the program is likely to drive more growth in the future.

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Tropical and Sub-tropical Regions to Drive Growth

Vector-borne illnesses are mostly caused by viruses, parasites, and bacteria. These are often transmitted through sandflies, mosquitoes, blackflies, triatomine bugs, tsetse, lice, mites, snails, and ticks. The suitable climate for growth of various species and changing agricultural practices are leading to an enormous growth of some of these transmitting species and subsequent illnesses. Additionally, factors like rising urbanization, adequate solid waste management, and lacking reliable piped water. Recent outbreaks like Zika virus, prevalence of malaria, and worsening climatic conditions are expected to result in more health precautions, and overwhelm health systems in several nations. The rising initiatives by organizations like WHO to support countries, provide key information for prevention, and innovation in various key anti-infective viral drugs are expected to drive growth.

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Mass Spectrometry in Protein Biomarker Market: Important Proteomic Technology in Biomarker Discovery

Protein biomarkers are indicators which are responsible for diagnosis and treatment of different diseases, mainly, cancer. These proteins may leak from tumors to body fluids and lead to early diagnosis.

These protein biomarkers are used in diagnostic purpose as well as several research studies such as drug discovery and potential treatment option for cancer

Protein biomarkers need to be discovered for these cancer diagnosis, research, and treatment purposes. This biomarker discovery stage is followed by verification and validation steps in biomarker pipeline.

Report Overview @ https://www.transparencymarketresearch.com/mass-spectrometry-in-protein-biomarker-market.html

In discovery and verification stages, both mass spectrometry and combination of liquid chromatography and mass spectrometry can be used. Mass spectrometry has greater importance in biomarker pipeline and biomarker studies.

Key Drivers and Restraints of Global Mass Spectrometry in Protein Biomarker Market

Rise in prevalence of cancer across the world and increase in demand for protein biomarker in different disease diagnosis and treatment are some of the major factors responsible for the growth of global mass spectrometry in protein biomarker market

For instance, according to the WHO, cancer was responsible for an estimated 9.6 million deaths and was the second major cause of death globally in 2018. It is estimated that around 1 in 6 deaths occur due to cancer at global level.

Advancement of mass spectrometry instruments coupled with software is also one of the major factors attributed for the growth of global mass spectrometry in protein biomarker market

Different strategic collaborations, mergers & acquisitions among major companies and research institutes for research purpose is also propelling the global mass spectrometry in protein biomarker market

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Higher Cost of Research Activities to Hamper Mass Spectrometry in Protein Biomarker Market

It takes very high cost or expenditure for research activities of biomarker in cancer and other related studies. Hence, lack of pharmaceutical & biotechnology companies’ capability for biomarker research due to cost factor may hinder the growth of global mass spectrometry in protein biomarker market.

Lower reproducible results associated with protein assays are also a problem as these assays exhibit less reproducibility due to day-to-day variability because of multiple steps in bottom-up proteomic process.

Mass Spectrometers to be Dominant segment

Based on product type, the global mass spectrometry in protein biomarker market can be segmented into mass spectrometers, accessories, and software

Mass spectrometers dominated the global market, owing to increase in demand of instrument in proteomics and growing application in cancer research

The mass spectrometer segment is further sub-segmented into MALDI-TOF MS, Triple Quadrupole MS, Quadrupole-Trap MS, Hybrid Linear Trap Orbitrap MS, and Quadrupole-Orbitrap MS

Triple Quadrupole MS is expected to be a highly lucrative sub-segment during the forecast period, owing to its features which are relatively simple and easy-to-use with good reproducibility to offer various applications at a low cost
Research & Development Application Segment to be Highly Lucrative Segment

In terms of application, the global mass spectrometry in protein biomarker market can be divided into diagnostics, research & development, therapeutics, and others
The diagnostic segment is anticipated to dominate the mass spectrometry in protein biomarker market during the forecast period. Rise in number of cancer cases across the world and increase in trend for early disease detection by advanced diagnostic procedures are some of the major factors responsible for the growth of this segment.

The research & development segment is projected to be a lucrative segment of the global market, owing to increase in number of research activities and search of new drugs for different conditions

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Life Sciences Companies Segment to be More Promising

Based on end-user, the global mass spectrometry in protein biomarker market can be segmented into diagnostic centers, life sciences companies, and academic & research institutes

The life sciences companies segment is anticipated to be a more promising segment in the next few years due to growth in research activities and rise in search for drug discovery and new molecules by these companies
North America to Lead Global Mass Spectrometry in Protein Biomarker Market

In terms of region, the global mass spectrometry in protein biomarker market can be divided into: North America, Europe, Asia Pacific, Latin America, and Middle East & Africa

North America dominated the global mass spectrometry in protein biomarker market in 2018, owing to higher prevalence of cancer, higher demand of biomarkers for disease diagnosis, presence of major players engaged in mergers & acquisitions, collaboration with CROs for biomarkers, and rise in investment for R&D by companies

For instance, in August 2017, BioIVT acquired Asterand Bioscience which was focused on drug research by biomarker validation and target identification
The mass spectrometry in protein biomarker market in Asia Pacific is expected to grow with a high CAGR during the forecast period, owing to large patient pool of cancer, increase in research activities, and improving health care infrastructure in the region

Key Manufacturers Operating in Global Mass Spectrometry in Protein Biomarker Market

Key manufacturers operating in the global market are:

Thermo Fisher Scientific Inc.
Agilent Technologies, Inc.
GE Healthcare
Bruker Corporation
Advion, Inc.
IONICON
Shimadzu Corporation
PerkinElmer Inc.
LECO Corporation
DH Tech. Dev. Pte. Ltd.

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Transparency Market Research has published a latest report that talks in detail about the global albumin market. According to the research report, the global albumin market is expected to reach a valuation worth US$1200 mn by the end of 2026. To achieve this valuation, the market is expected to grow at a rate of 5% CAGR over the course of the given forecast period of 2018 to 2026.

Asia Pacific Region to Showcase Maximum Growth Potential

According to the research report, the Asia Pacific region is expected to show maximum growth potential as compared to the other regional segments of North America, Latin America, Europe, and Middle East and Africa. The growth of the Asia Pacific region is high because of the growing demand for albumin in countries such as India and China. However, the rate of adoption is slightly lower due to lack of awareness and benefits of the product and its therapeutic benefits. Precisely keeping this in mind, the government and healthcare regulatory bodies have initiated several awareness campaigns. This has been particularly helpful for the growth of the albumin market in the region. Organization such as PPTA have conducted awareness programs such as International Plasma Awareness Week to aid in boosting the awareness about donation of plasma. It also raised awareness about the different therapeutic benefits of and plasma protein therapies available in the market. This has thus helped in the overall development of the albumin market in the Asia Pacific region.

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The biotechnology and pharmacy industry segment is expected to dominate the global albumin market in the coming years of the forecast period. The segment was initially valued at US$500 mn in the year 2017. The growing research and development activities across the industry is helping to drive the growth of the global albumin market. This coupled with the growing investments provided by both private as well as public sector is also expected to help in the growth of the global albumin market.

Drug Delivery Segment to Continue to Dominate

The drug delivery segment accounts for nearly 25% of the overall market share in 2017. This trend is projected to continue over the course of the given forecast period. The usage of human serum albumin nanoparticles as a favored drug delivery system with applications for a wide range of diseases is expected to help the growth of the global market. The ongoing collaborations and joint ventures among the leading manufacturers in the global albumin market is expected to provide significant boost to the growth of the market. For example, in May 2015, Serendex Pharmaceutical announced that the company has initiated the phase I trials of Molgradex. This drug candidate is used for treating rare pulmonary diseases. The drug uses Novozymes’ Recombumin, a recombinant human albumin for more effective delivery of the therapeutic to the lungs.

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The competitive landscape of the global albumin market is a consolidated one and features only a handful of leading players. Some of the big names in the global albumin market include names such as Octapharma AG, Baxter, Grifols International SA, and CSL Behring LLC. The newer and promising entrants in the albumin market refer to the established brands that are keen on developing and manufacturing albumin as an excipient. Moreover, the leading players in the market are adopting strategies such as merger, acquisitions, and joint ventures to stay ahead of the competitive curve.

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The global chemiluminescence immunoassay (CLIA) analyzers market was valued over US$ 4.4 Bn in 2016 and is projected to register cumulative annual growth rate (CAGR) of over 6.0% from 2017 to 2025, according to a new report published by Transparency Market Research (TMR) titled “Chemiluminescence Immunoassay (CLIA) Analyzers Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2017–2025”. The report suggests that rising demand for international accreditations and result comparability by using high-throughput automated immunoassays is spurring the growth of chemiluminescence immunoassay (CLIA) analyzers in coming years (2017 to 2025).

The North America and Europe are projected to dominate the global chemiluminescence immunoassay (CLIA) analyzers market in the coming years owing to increase in manufacturer focus for business expansion in these regions. Players are continuously developing multiplexed assay platforms and entering into distribution agreements to fortify their footprints in the North American and European markets. Growing adoption of technologically advanced products manufactured by local manufacturers like Shenzhen New Industries Biomedical Engineering Co., Ltd. is likely to drive the Asia Pacific chemiluminescence immunoassay (CLIA) analyzers market. The Asia Pacific chemiluminescence immunoassay (CLIA) analyzers market is expected to witness CAGR of over 6.5% from 2017 to 2025

Reagents Dominates the Market Followed by Automated Analyzers

The report offers detailed segmentation of global chemiluminescence immunoassay (CLIA) analyzers market based on product, application, and end-user. Among the product segment, reagents segment is poised to account for leading share of the global market during the forecast period from 2017 to 2025. Factors attributed to the higher share of the reagent segment in the global market include frequent replacements leading to increasing usage of reagents when compared to analyzer platforms. Automated analyzers segment is likely to register comparatively higher growth rate in terms of value in the global chemiluminescence immunoassay (CLIA) analyzers market during the forecast period owing to continuous innovations in the product technologies by major market players.

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Endocrine Disorders & Oncology: Top Two Application Areas of Chemiluminescence Immunoassay (CLIA) Analyzers

Among applications, endocrine disorders segment is projected to hold dominant share of global chemiluminescence immunoassay (CLIA) analyzers market during the forecast period and is likely to expand at CAGR more than 6.0% from 2017 to 2025. Major factors responsible for the dominance of this segment are continuous innovations in test offerings and wide product portfolio of major as well as local manufacturers.

For instance, in January, 2017, the world's first assay to measure free vitamin D was introduced by Future Diagnostics Solutions and DIAsource Immunoassays SA (Anteo Group). Such continuous new product launches, along with exponentially rising patient base in developed as well as developing countries are likely to drive the segment between 2017 and 2025. According to the National Institute of Diabetes & Digestive and Kidney Diseases in the U.S., nearly 4.6% of the U.S. population suffers from hypothyroidism, which highlights the significant need for advanced testing methods to diagnose the endocrine disorder. Hepatitis and retrovirus segment, accounted for more than 10.0% share of global chemiluminescence immunoassay (CLIA) analyzers market in 2016, in terms of value. It is anticipated to have substantial growth and account for approximately 12.0% of market share by 2025.

Growth of the Asia Pacific Chemiluminescence Immunoassay (CLIA) Analyzers Market Likely To Be Hinged At China, India

In terms of value, North America is likely to continue its dominance in the global chemiluminescence immunoassay (CLIA) analyzers market throughout the forecast period, owing to significant average selling prices of automated chemiluminescence immunoassay analyzers, rising demand from physicians for technologically advanced diagnostic instruments with enhanced specificity and precision, and favorable coverage as per the Clinical Laboratory Improvement Amendments for in-vitro diagnostic procedures in the region. Latin America and Middle East & Africa are relatively untapped markets having high growth potential. The governmental cap on prices of analyzers and group purchasing policies by major multispecialty hospital chains in this region is further increasing adoption of rental CLIA analyzers in these regions. Middle East & Africa chemiluminescence immunoassay (CLIA) analyzers market is characterized with significant population base demanding affordable care, and rise in governmental initiatives for early diagnosis of these chronic diseases. For instance, as per UNAIDS publication in 2016, nearly 65% of the world’s HIV infected population are present in this region.

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Highly Consolidated Market With Top Three Players Accounting For More Than 50.0% of the Global Market

The report also provide profiles of leading players operating in global chemiluminescence immunoassay (CLIA) analyzers market. F. Hoffmann-La Roche Ltd., Abbott, Siemens Healthineers, and Beckman Coulter, Inc. (Danaher) are major players operating in the market, offering products with proprietary technologies, such as F. Hoffmann-La Roche Ltd.’s products are manufactured using proprietary electrochemiluminescence technology, while Abbott’s CLIA analyzers are manufactured using the chemiluminescent microparticle immunoassay technology. DiaSorin S.p.A. and Shenzhen New Industries Biomedical Engineering Co., Ltd. are the other major players in the developed and developing countries, respectively.

Expansion of tests offering in integrated digital diagnostics platform through partnerships to improve oncology and critical care treatment is a growing trend in global chemiluminescence immunoassay (CLIA) analyzers market. For instance, in January 2018, F. Hoffmann-La Roche Ltd. and GE Healthcare entered into strategic partnership to develop an industry-first digital platform, which will provide digital clinical decision support solutions in oncology and critical care treatment. Other prominent players in the global chemiluminescence immunoassay (CLIA) analyzers market include Sysmex Corporation, Randox Laboratories Ltd., Ortho Clinical Diagnostics (a part of Carlyle Group), and Tosoh Corporation.

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Blood Pressure Monitoring Devices & Accessories Market: Introduction

Transparency Market Research has published a new report titled, ‘Global Blood Pressure Monitoring Devices & Accessories Market’. According to the report, the global blood pressure monitoring devices & accessories market was valued at ~US$ 1.9 Bn in 2018 and is projected to expand at a CAGR of ~7% from 2019 to 2027.

The medical term for high blood pressure is hypertension. Blood pressure is considered to be normal under a systolic value of 140 mmHg and under a diastolic value of 90 mmHg. A blood pressure monitoring device reads blood pressure automatically based on variations in the volume of blood in the arteries. Systolic and diastolic are terms used to depict or interpret blood pressure. The blood pressure is measured in terms of millimeters of mercury (mmHg). The three stages of hypertension are prehypertension (from 120-139 over 80-90), stage 1 (from 140-159 over 90-99), and stage 2 (from 160 and above over 100 and above).

Blood Pressure Monitoring Devices & Accessories Market: Major Segments

In terms of device, the global blood pressure monitoring devices & accessories market has been segmented into sphygmomanometers, automatic blood pressure monitors, ambulatory blood pressure monitors, blood pressure transducers, and blood pressure instrument accessories. Sphygmomanometers have been categorized into mercury sphygmomanometers, aneroid sphygmomanometers, and digital sphygmomanometers. Blood pressure transducers has been classified into disposable and reusable.

Blood pressure instrument accessories have been split into blood pressure cuffs, and bladders, bulbs, and valves. The automatic blood pressure monitors segment is projected to dominate the global market during the forecast period, owing to increase in usage in different types of surgeries for different indications. User-friendliness and safe application are the major advantages of these devices. The segment held significant share of the global blood pressure monitoring devices & accessories market in 2018. The automatic blood pressure monitors segment is anticipated to expand at a moderate CAGR between 2019 and 2027, owing to rise in surgeries and adoption rate of self-serving diagnostic tools.

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Sphygmomanometers are the other most preferred blood pressure monitors, as these are cost-effective and offer accurate readings. Growth of the sphygmomanometers segment is likely to be stable owing to decline in usage of mercury sphygmomanometers, introduction of large number of aneroid sphygmomanometers in the market, and rise in digitalization in the readings of blood pressure monitors. The blood pressure transducers and blood pressure instrument accessories segments are anticipated to witness moderate growth during the forecast period. High accuracy of blood pressure transducers, increase in the geriatric population, and favorable trade regulations in the developing countries are the major factors expected to propel the blood pressure transducers and blood pressure instrument accessories segments during the forecast period.

Based on end user, the global blood pressure monitoring devices & accessories market has been divided into hospitals, ambulatory surgical centers, clinics, home care settings, and others. The home care settings segment captured the largest market share in 2018, owing to the availability of trained & qualified personnel and favorable reimbursement structure.

The segment is expected to expand at the highest CAGR during the forecast period, attributed to the miniaturization of devices and rise in need & demand for self-testing devices by patients. Increase in the geriatric population and improvements in healthcare facilities in developing countries are anticipated to propel the clinics segment during the forecast period. However, rise in need & demand for blood pressure kiosks at public places (gym, airports, colleges, etc.) and government funding to boost the production of blood pressure monitors are likely to augment the ambulatory surgical centers and others segments during the forecast period.

Blood Pressure Monitoring Devices & Accessories Market: Prominent Regions

North America held major share of the global blood pressure monitoring devices & accessories market in 2018. Highly structured health care industry, presence of key players, and growth strategies of these players are the major factors driving the market in the region. Rise in awareness about the benefits of surgeries and procedures and increase in healthcare expenditure also contribute to the growth of the market in North America.

Asia Pacific held the second largest share of the global blood pressure monitoring devices & accessories market in 2018. Growth of the blood pressure monitoring devices & accessories market in the region can be attributed to rise in prevalence of chronic diseases and well-developed healthcare sector in the region. The market in Asia Pacific is expected to grow at a rapid pace during the forecast period. Increase in number of people with cardiovascular diseases, product approvals, and rise in awareness about cardiovascular diseases are factors anticipated to fuel the growth of the blood pressure monitoring devices & accessories market in the region.

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Blood Pressure Monitoring Devices & Accessories Market: Key Players

Key players are expanding their footprint to strengthen their positions in the global blood pressure monitoring devices & accessories market. Increase in population with hypertension offers lucrative opportunities to key players to increase their share in the blood pressure monitoring devices & accessories market. Hence, manufacturers are engaging in new product development, collaborations, and distribution to gain market share.

Leading players operating in the global blood pressure monitoring devices & accessories market include Omron Healthcare, Inc., Koninklijke Philips N.V., Schiller AG, American Diagnostic Corporation, SPENGLER, Spacelabs Healthcare, Withings SA, Welch Allyn, Inc., SunTech Medical, Inc., A&D Medical, and GE Healthcare.

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